Abstract：Objective: To investigate and compare predictive diagnostic value of TG/HDL-C, TC/HDL-C, non-HDL-C ratios for isolated post-challenge hyperglycemia (IPH). Methods: 220 patients with IPH and 216 normal glucose tolerances (NGT) were enrolled in this study. All subjects were underwent a75-g OGTT. Their clinical, lipid and glucose were measured and calculated TG/HDL-C, TC/HDL-C, non-HDL-C ratios. Results: Compared with NGT, patients with IPH had higher blood pressure, BMI, waist circumference, TC, TG, LDL-C,TG/HDL-C, TC/HDL-C,non-HDL-C and 2h-PG, with lower HDL-C (P<0.05). According to logistic regression analysis, after adjusted for the age, blood pressure, BMI, waist circumference and FBG, TC, TG, LDL-C, TC/HDL-C, TG/HDL-C, and non-HDL-C were all positively correlated with IPH. TG/HDL-C obtained the highest area under the curve (AUC) of 0.832 determined by ROC curves, suggesting that TG/HDL-C has the greatest diagnostic value of IPH. The cut off value of TG/ HDL-C was set at 1.42, with the sensitivity of 81.90% and the specificity of 69.20%. Conclusion: TG/HDL-C has the greatest diagnostic value of IPH, patients whose TG/HDL-C is over 1.42 need further test of OGTT in order to diagnose IPH earlier.
汤金梅, 毕亭亭, 周茜, 徐晓, 乔慧瑛, 杨绪枫, 吕荣. 血脂指标比值对单纯餐后高血糖型糖尿病的预测价值[J]. 河北医学, 2018, 24(2): 262-266.
TANG Jinmei, BI Tingting, ZHOU Qian, et al. The Predictive Value of the Ratio of Blood Lipid Index to Simple Postprandial Hyperglycemic Diabetes. HeBei Med, 2018, 24(2): 262-266.
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2018, Vol. 24 
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