不同麻醉方式对于乳腺癌术后中性粒细胞及淋巴细胞的影响

doi:10.3969/j.issn.1006-6233.2018.02.016

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摘要 目的: 观察全程静脉麻醉和静吸复合麻醉两种不同麻醉方式对于乳腺癌术后中性粒细胞及淋巴细胞的影响。方法: 采用前瞻性研究方法将100例行手术治疗的乳腺癌患者随机分为两组,A组(n=50)采用全程静脉麻醉,B组(n=50)采用静吸复合麻醉,比较手术前后的外周血中性粒细胞计数(N)、淋巴细胞计数(L)以及中性粒细胞/淋巴细胞比值(NLR)变化情况。结果: 两组患者手术前、手术后的血清N、L、NLR值差异有统计学意义(P均<0.05);两组患者手术后的N、L、NLR值差异无统计学意义(P均>0.05)。结论: 全程静脉麻醉和静吸复合麻醉两种不同麻醉方式对于乳腺癌术后的N、L、NLR值的影响轻微,建议根据患者的实际情况合理选择麻醉方式。

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关键词 ：乳腺癌, 全程静脉麻, 静吸复合麻醉, 中性粒细胞计数, 淋巴细胞计数, 中性粒细胞淋巴细胞比值

Abstract：Objective: To observe the suction compound anesthesia with intravenous anesthesia and two different anesthetic methods for breast cancer postoperative neutrophils and lymphocytes. Methods: A prospective study was conducted. 100 patients with breast cancer were randomly divided into two groups. Group A (n=50) received total intravenous anesthesia, group B (n=50) received static inhalation combined anesthesia. The changes of neutrophils count (N), lymphocyte count (L) and neutrophils / lymphocyte ratio (NLR) were compared before and after the operation. Results: There was significant difference in serum N, L and NLR values between the two groups before and after operation (P < 0.05). There was no significant difference in the value of N, L and NLR between the two groups after operation (P > 0.05). Conclusion: Two different ways of total intravenous anesthesia and intravenous inhalation combined anesthesia have slight effect on the N, L and NLR value of breast cancer after operation. It is suggested that anesthesia should be chosen according to the actual situation of patients.

Key words： Breast cancer Total intravenous anesthesia Static absorption compound anesthesia Neutrophil count Lymphocyte count Neutrophils lymphocyte ratio

基金资助:四川省医学科研课题,(编号:S16002)

通讯作者: 刘斌

引用本文:

凌华, 刘斌, 谢先丰, 刘少星, 孙燕. 不同麻醉方式对于乳腺癌术后中性粒细胞及淋巴细胞的影响[J]. 河北医学, 2018, 24(2): 242-245.
LING Hua, et al. Effects of Different Anesthetic Methods on Neutrophils and Lymphocytes after Breast Cancer Surgery. HeBei Med, 2018, 24(2): 242-245.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2018.02.016 或 http://www.hbyxzzs.cn/CN/Y2018/V24/I2/242

[1] 张丽红,董学君,王宏斌.应用红细胞分布宽度判断乳腺癌转移[J].中国卫生检验杂志,2015,25(18):3133~3134.
[2] 张慧,赵瑞珂,顾国浩,等.乳腺癌患者部分外周血生化指标的变化及其意义[J].检验医学与临床,2016,13(15):2153~2155.
[3] 詹妍,王文博,周福祥,等.中性粒细胞/淋巴细胞比值在乳腺癌预后评估中的应用[J].武汉大学学报,2013,34(3):391~394.
[4] 周际昌.实用肿瘤内科学[M].第2版.北京:人民卫生出版社,2003.152~153.
[5] 莱斯利·索宾,玛丽·高斯伯德罗维兹,克里斯坦·维特金德(编著),周清华,孙燕(翻译).恶性肿瘤TNM分期[M].第7版.天津:天津科技翻译出版公司,2012.182~193.
[6] 陈茂山,张艳利,杨宏伟,等.外周血中性粒细胞与淋巴细胞比率和血小板与淋巴细胞比率对乳腺癌新辅助化疗疗效的预测价值[J].肿瘤学杂志,2017,23(3):180~184.
[7] 钱鹏,恽华忠,朱玲,等.炎性指标在乳腺癌术前诊断和预后评估中的价值[J].检验医学与临床,2015,12(24):3765~3767.
[8] 王宁舫,洪群英.肺癌转移的炎症微环境机制研究进展[J].国际呼吸杂志,2014,34(24):1905~1908.
[9] 王智,马晋平,林建伟,等.术前中性粒细胞与淋巴细胞比值与结直肠癌患者预后的关系[J].消化肿瘤杂志(电子版),2011,3(4):246~250.
[10] Sato H,Tsubosa Y,Kawano T.Correlation between the prethera-peutic neutrophil to lymphocyte ratio and the pathologic response toneoadjuvant chemotherapy in patients with advanced esophagealcancer[J].World J Surg,2012,36(3):617~622.
[11] 石鹏,赵毅,邓鑫.术前中性粒细胞淋巴细胞比率(LR)预测胃癌预后的临床意义[J].现代肿瘤学,2012,20(5):987~989.
[12] 胡赟宏,王铮元,崔嵘嵘,等.中性粒细胞/淋巴细胞比值与血小板/淋巴细胞比值对乳腺癌复发转移的预测价值及乳腺癌预后影响因素研究[J].中国全科医学,2016,19(30):3657~3661.