右美托咪定对高血压患者全身麻醉拔管期心率收缩压乘积和血压心率比值的影响

doi:10.3969/j.issn.1006-6233.2017.09.023

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摘要 目的: 观察右美托咪定对高血压患者全身麻醉拔管期心率收缩压乘积(RPP)和血压心率比值(PRQ)的影响。方法: 选择97例需行全麻手术且合并有高血压的患者作为研究对象,所有患者均给予常规麻醉,随机将其分为两组,观察组(n=49)在术前30min静脉注射0.5μg/kg右美托咪定,对照组(n=48)在相同时刻静脉注射等量生理盐水,对比两组患者给药前(T0)、拔管前(T1)、拔管时(T2)、拔管后5min(T3)、拔管后10min(T4)的HR、SBP、DBP、MAP等指标,计算RPP和PRQ差异情况。结果: 观察组T1、T2时的HR显著低于对照组(P均＜0.05),T1、T2、T3的SBP、DBP、MAP显著低于对照组(P均＜0.05);观察组的T1~T4的RPP显著低于对照组(P均＜0.05),但两组T0~T4的PRQ比较差异无统计学意义(P均＞0.05);两组患者在研究时间均未见严重不良反应。结论: 右美托咪定可以有效降低高血压患者全身麻醉拔管期的RPP,保证更好的血流动力学指标稳定性和更低的心血管反应,提高拔管质量。

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关键词 ：全身麻醉, 高血压, 右美托咪定, 心率收缩压乘积, 血压心率比值

Abstract：Objective: To observe the tora microphones set decannulation period of general anesthesia in patients with high blood pressure heart rate, systolic blood pressure product (RPP) ratio (PRQ) the effects of heart rate and blood pressure.Method: Choose 97 cases of general anesthesia, surgery combined with hypertension patients as the research object, all the patients were given general anesthesia, it can be divided into two groups at random, the observation group (n = 49) in preoperative 30 min intravenous 0.5 mu g/kg right beautiful mi set, the control group (n = 48) intravenous injection amount of normal saline in the same time, compared two groups of patients with medication (T0), tube drawing before (T1), when the tube drawing (T2), 5 min after extubation (T3), 10 min after extubation (T4) HR, SBP, DBP, MAP and other indicators, calculate the RPP and PRQ differences.Results: Observation group T1, T2 of HR was significantly lower than control group (P <|0.05), T1, T2, T3, SBP, DBP, MAP was significantly lower than the control group (P <|0.05);Observation group of T1 ~ T4 RPP was significantly lower than the control group (P <|0.05), but the T0 ~ T4 PRQ was similar between the two groups had no statistical significance (P >|0.05);Two groups of patients in the study were no serious adverse reaction.Conclusion: Right beautiful mi set which can effectively reduce the high blood pressure patients decannulation period of general anesthesia RPP, guarantee better stability and lower cardiovascular hemodynamic parameters reaction, improve the quality of tube drawing.

Key words： General anesthesia High blood pressure Beauty's right of egypt Product of heart rate systolic blood pressure Blood pressure heart rate ratio

基金资助:中山市医学科研基金项目,(编号:20102C159)

引用本文:

程周, 廖小卒, 王立强, 陈勇, 黄锡强. 右美托咪定对高血压患者全身麻醉拔管期心率收缩压乘积和血压心率比值的影响[J]. 河北医学, 2017, 23(9): 1487-1489.
CHENG Zhou, LIAO Xiaozu, WANG Lijiang, et al. Beauty's Microphones Set Right Decannulation Period of General Anesthesia in Patients with High Blood Pressure Heart Rate, Systolic Blood Pressure Product (RPP) Ratio (PRQ) the Influence of Heart Rate and Blood Pressure. HeBei Med, 2017, 23(9): 1487-1489.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2017.09.023 或 http://www.hbyxzzs.cn/CN/Y2017/V23/I9/1487

[1] 梁维,熊威威,王华.低剂量右美托咪定对全麻高血压手术患者血流动力学和麻醉效果的影响[J].实用药物与临床,2015,18(10):1211~1213.
[2] 康于庆,冷玉芳,薛兴,等.右美托咪定对高血压患者全麻气管拔管反应及苏醒时间的影响[J].临床麻醉学杂志,2011,27(8):800~802.
[3] 李继周,薛利军,边步荣,等.右美托咪定预防腹腔镜子宫切除术患者麻醉并发症的临床研究[J].中国临床研究,2015,28(2):217~219.
[4] 庄心良,曾因明,陈伯銮.现代麻醉学[M].第3版.北京:人民卫生出版社,2003.1024~1026.
[5] 夏勇军,李军鹏,李萌,等.右美托咪定联合地佐辛对老年高血压患者全麻苏醒期躁动及血流动力学的影响[J].临床麻醉学杂志,2015,31(7):647~651.
[6] 罗颖,周小莲,金芊芊,等.右美托咪定对老年高血压患者全麻拔管期应激反应及苏醒时间的影响[J].中华全科医学,2014,12(2):171~173.
[7] 戴双波,古妙宁,齐娟.右美托咪定对高血压患者全身麻醉拔管期RPP和PRQ的影响[J].临床麻醉学杂志,2014,30(2):125~127.
[8] 林丽,陆元霄,邵秀霞.右美托咪定改善高血压患者全麻拔管期RPP和PRQ初步评价[J].全科医学临床与教育,2015,13(2):184~187.
[9] 顾国华,冯兆明,朱俊峰.右美托咪定对老年高血压患者围术期心肌的保护作用[J].临床麻醉学杂志,2011,27(8):797~798.
[10] 高静丹.右美托咪定对老年患者全身麻醉拔管期的血压心率比值影响[J].现代医药卫生,2015,31(2):261~263.
[11] 李淑霞,杨亚琴,张丽霞.右美托咪定对高血压患者全麻气管拔管期RPP、PRQ和苏醒时间的影响[J].中国临床研究,2016,29(5):650~652.
[12] 尹加林,戴琼艳,谢欣怡,等.麻醉恢复期的管理专辑三种不同剂量右美托咪定对全麻鼻内镜手术围拔管期应激反应的影响[J].临床麻醉学杂志,2014,30(10):941~945.