Abstract：Objective: To analyze the clinical effect of nasal endoscopic perforation repair on patients with nasal septum perforation. Methods: 60 patients with nasal septum perforation admitted to our hospital from May 2015 to May 2017 were randomly divided into control group (n = 30) and observation group (n = 30) according to the random number table method. Thirty patients in the control group were treated by conventional repair surgery. Thirty patients in the observation group were treated with endoscopic nasal septal mucosal flap repair. The clinical effects of the two groups were compared. Results: The success rate of repair in the observation group was 93.33% (28/30), while that in the control group was 73.33% (22/30), with significant difference (χ2= 4.320, P <0.05) The patients' operation time, intraoperative blood loss, postoperative mucosal repair time and mucosal injury range were (46.18 ± 8.42) min, [(12.69 ± 2.54) mL], [(29.35 ± 4.72) 20.38 ± 5.26) mm2]. The patients in the observation group had a significant reduction of operation time, intraoperative blood loss, postoperative mucosal repair time and the range of mucosa damage [(25.46 ± 5.09) min], [(3.87 ± 1.17) mL] 18.68 ± 3.54) d] and [(10.64 ± 4.02) mm2] respectively. There were significant differences in the above indexes between the two groups (t = 11.535,17.275,9.905,8.058;P <0.05) The incidence of postoperative complications was significantly lower than that of the control group, and the I-phase healing rate in the observation group was significantly higher than that in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion: Nasal septal perforation in patients undergoing endoscopic nasal septal perforation repair surgery can effectively shorten the operation time and reduce intraoperative bleeding, the patient's healing effect is good, the incidence of complications is lower, higher safety, with higher The clinical promotion value.
[1] 董龙宝,薛洁,田振华.鼻内窥镜下带蒂鼻中隔黏骨膜瓣转位联合游离下鼻甲粘膜修补鼻中隔穿孔[J].中医耳鼻喉科学研究,2017,24(1):57~58. [2] 唐玲,徐先发.鼻腔底带蒂黏膜瓣联合下鼻甲带蒂黏膜瓣修补鼻中隔穿孔[J].中华耳鼻咽喉头颈外科杂志,2017,52(2):106~108. [3] Ilteris Murat Emsen.A different approach to the reconstruction of nasal septum perforations:alar winged flap[J].Journal of Craniofacial Surgery,2015,26(8):698~702. [4] 路鹏,崔晓光.鼻内镜下应用三层移植物修补鼻中隔穿孔的临床疗效[J].河北医学,2016,22(8):1330~1332. [5] 董龙宝,薛洁,田振华.鼻内镜下带蒂鼻中隔黏骨膜瓣转位联合游离下鼻甲黏膜瓣修补鼻中隔穿孔[J].中国中西医结合耳鼻咽喉科杂志,2015,23(6):420~421. [6] Menghang Wang,Lisheng Yu.Transplantation of adipose-derived stem cells combined with decellularized cartilage ECM:A novel approach to nasal septum perforation repair[J].Medical Hypotheses,2014,82(6)781~783. [7] 李惠,王俊国,钱晓云等.鼻内镜下鼻中隔软骨、筛骨垂直板或耳屏软骨修补鼻中隔穿孔[J].现代生物医学进展,2017,17(14):2766~2769. [8] Annika Meyer,Mary Czerny,Jastin Antisdel.Nasal mucosa ulceration and septal perforation as initial presentation of a patient with probable behcet's disease[J].International Journal of Pediatric Otorhinolaryngology Extra,2014,9(2)56~59. [9] 朱先柏,霍宇,刘英祥.鼻内镜下行鼻中隔穿孔修补术的技巧与难点分析[J].重庆医学,2014,43(20):2647~2649. [10] 路鹏,崔晓光.鼻内窥镜下应用异种脱细胞真皮基质修补鼻中隔穿孔的临床效果研究[J].河北医学,2017,23(6):994~997. [11] Robert J,Taylor,David A,et al.Prosthetics for nasoseptal perforations[J].Otolaryngology--Head and Neck Surgery,2015,152(5):803~810.
2018, Vol. 24 
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