Abstract：Objective: To observe the risk factors of vascular cognitive impairment(VCI) in acute cerebral infarction patients. Methods: A total of 100 cases of acute cerebral infarction patients were divided into VCI group (64 cases) and non-VCI group (36 cases) according to the presence of VCI. Then single factor and multi-factor analysis were implemented in the VCI among acute cerebral infarction patients. Result: No statistical significance was observed in smoking, drinking and arterial fibrillation between the two groups (p>0.05); while the statistical significances were obtained in comparisons of carotid artherosclerosis, primary hypertension, leukoaraiosis, diabetes and serum Hcy level between groups (p<0.05). The multivariable Logistic regression model revealed that the serum Hcy level [OR=0.520,95%Cl:1.120~1.014,P=0.001], leukoaraiosis [OR=6.833,95%Cl:2.474~12.365,P=0.002], primary hypertension[OR=2.671,95%Cl:1.031~7.120,P=0.011], carotid artherosclerosis [OR=3.319,95%Cl:1.225~8.669,P=0.040] and diabetes [OR=7.131,95%Cl:2.029~19.322,P=0.001] were all closely related to the presence of VCI in acute cerebral infarction patients. Conclusion: For patients with acute cerebral infarction, theses conditions such as diabetes, carotid atherosclerosis, primary hypertension, leukoaraiosis, and serum Hcy concentration may be considered as a hint for cognitive dysfunction.
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2018, Vol. 24 
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