Abstract：Objective:To investigate the clinical effect of target controlled infusion of sevoflurane combined with remifentanil in elderly patients with cancer. Methods: From January 2015 to August 2017, 98 elderly patients undergoing general anesthesia were divided into observation group and control group according to different anesthesia regimens. The patients in the control group were anesthetized with propofol combined with seven flurane target controlled infusion. The patients in the observation group were anesthetized with remifentanil combined with target controlled infusion of seven halothane. The changes of vital signs before and after anesthesia were observed in two groups, and the postoperative waking time and extubation time were compared and analyzed. Results:The systolic blood pressure, diastolic blood pressure and MAP of observation group and control group were significantly different from those of T0 (P<0.05), but at T0, T1, T2 and T3, systolic blood pressure, diastolic blood pressure, heart rate and MAP level were not significantly different (P>0.05). The awake time and extubation time in the observation group were significantly shorter than those in the control group, the difference was significant (P<0.05). Conclusion: Targeted infusion of sevoflurane combined with remifentanil in elderly patients with tumor surgery can achieve a good anesthetic effect while shortening the recovery time of patients after surgery, is conducive to follow-up treatment and care, it is recommended in the clinical application .
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2018, Vol. 24 
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