Abstract:Objective: To observe the effect of OLYMPUS BF3C-40 type electron fiber bronchoscopy in the treatment of children with refractory Mycoplasma pneumoniae pneumonia. Methods: Sixty children with refractory mycoplasmalpneumonia were divided into the medicine group and the electron branchofiberoscope group (30 cases in each group) The medicine group was given antiinfection, ntipyretic, and relieve cough medicine. The electron branchofiberoscope was added in the electron branchofiberoscope group, the clinical effect were observed in two groups. Results: The cough duration, moist rales, and hospitalization time were significantly shorter in the electron branchofiberoscope group (t=3.87, 3.67, 7.65, P<0.05). After treatment, the difference of CRP, WBC, ESR among two groups were significantly better in the electron branchofiberoscope group, there were significant difference (t=1.12, 1.03, 1.17;t=2.33, 2.47,3.58;t=1.65,3.13,3.93, P<0.05). The total effective rate in the electron branchofiberoscope group were significantly higher than that in the drug group (χ2=10.708,P< 0.05). Conclusion: The electron branchofiberoscope lavage therapy can significantly improve the effect of treatment in children with refractory mycoplasmal pneumonia and improve the symptom in the lung.
[1] 陈嘉慧,印根权,余嘉璐,等.红霉素与阿奇霉素治疗小儿肺炎支原体肺炎的临床研究[J].中国临床药理学杂志,2015,24(8):587~589. [2] Zhang Z J, Center E, Hospital S P. The application of clinical nursing pathway in fiber bronchoscope[J]. Chinese Journal of General Practice, 2016,12(10):87~93. [3] 中华医学会儿科学分会呼吸学组.儿童社区获得性肺炎管理指南(2013修订)(下)[J].中华儿科杂志,2013,51(11):856~862. [4] Liu J. Curative effect of branchofiberoscope lavage in the treatment of pneumonia with sepsis patients[J]. Labeled Immunoassays & Clinical Medicine, 2016,21 (3):67~72. [5] Jiang Y H, Yu J E, Guo A H, et al. Ameliorative effects of qingfei tongluo formula on experimental mycoplasmal pneumonia in mice[J]. Journal of Natural Medicines, 2016, 70(2):145~151. [6] Guo H, He Z, Li M, et al. Imbalance of peripheral blood Th17 and Treg responses in children with refractory mycoplasma pneumoniae pneumonia.[J]. Journal of Infection & Chemotherapy Official Journal of the Japan Society of Chemotherapy, 2016, 22(3):162~166.