Effect of Perioperative Fast Track Surgery (FTS) on Postoperative Inflammatory Stress Reaction and Prognosis in Patients with Colorectal Cancer and Diabetes Mellitus
HE Fang, BIAN Yajin, CHANG Weiwei
The Second Hospital of Qinhuangdao, Hebei Qinhuangdao 066600, China
Abstract：Objective: To investigate the effect of perioperative fast track surgery (FTS) on postoperative inflammatory stress reaction and prognosis in patients with colorectal cancer and diabetes mellitus. Methods: According to the random number table method,eighty patients with colorectal cancer and diabetes mellitus were divided into two groups:the control group(D group)and the observation group (F group).The patients in the control group were performed with routine perioperative treatment,while the patients in the observation group were given FTS perioperative treatment.Prognosis and the difference of postoperative inflammatory stress reaction between the two groups were observed.Results: Therewere no significant differences in age and duration of diabetes between the two groups(P<0.05).The defecation time,anal exhaust time,wound healing time and hospitalization time in group F were significantly shorter than those in group D (P<0.05).At the same time,the weight,hemoglobin and albumin reduction of group F were significantly lower than those in group D (P<0.05);The incidence of postoperative complications in group F (7.50%) was significantly lower than that in group D (32.50%) (P<0.05),and the level of inflammation index (CRP,IL-6,SAA,TNF- a) in group F was significantly better than that in group Dat postoperative 5 days (P<0.05). Conclusion: It is of great significance to reduce the incidence of complications,control the level of inflammation,shorten the time of rehabilitation and improve the prognosis by using the FTS concept for the perioperative management of colorectal carcinomacomplicated with diabetes mellitus.
何方,卞雅金,常伟伟. 围术期快速康复外科干预对结直肠癌合并糖尿病的患者术后炎性应激反应及预后的影响[J]. 河北医学, 2018, 24(12): 2026-2028.
HE Fang, BIAN Yajin, CHANG Weiwei. Effect of Perioperative Fast Track Surgery (FTS) on Postoperative Inflammatory Stress Reaction and Prognosis in Patients with Colorectal Cancer and Diabetes Mellitus. HeBei Med, 2018, 24(12): 2026-2028.
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2018, Vol. 24 
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