Abstract：Objective: To study the diagnostic value of the change of Serum PCT, SAA and CRP in biliary fistula after intrahepatic biliary calculi operation. Methods: The 232 cases with surgery of intrahepatic biliary calculi treated from April, 2015 to April, 2017 in our hospital, which were selected as the research objects, according to whether or not occuring the biliary fistula,were divided into the group of biliary fistula(21 cases) and non- biliary fistula(211 cases). The levels of PCT, SAA and CRP in the two groups were detected one day before operation, and one day after operation, two days after operation, three days after operation respectively. And then we compared th test. Results: No significant difference was found between the patients one day before operation and one day after operation in two groups on serum levels of PCT, SAA and CRP(P>0.05). But the patients two days after operation and three days after operation in the group of biliary fistula were higher than those of non- biliary fistula group, the difference had statistically significant(P<0.05). Conclusion: When patients in biliary fistula after intrahepatic biliary calculi operation, PCT, SAA and CRP levels have significantly elevated, which had significant assist of diagnostic value.
陈国利,傅华,张学军. PCT SAA和CRP联合检测对肝内外胆管结石术后胆瘘的诊断价值[J]. 河北医学, 2018, 24(11): 1870-1873.
CHEN Guoli, FU Hua, ZHANG Xuejun. Diagnostic Value of the Change of Serum PCT SAA and CRP in Biliary Fistula after Intrahepatic Biliary Calculi Operation. HeBei Med, 2018, 24(11): 1870-1873.
[1] Chuan Li, Tianfu Wen. Surgical management of hepatolithiasis: a minireview[J]. Intractable Rare Dis Res,2017,6(2):102~105. [2] 杨晓龙,李蒙.肝胆手术后出现胆瘘的原因分析[J].中国医药指南,2013,11(19):508~509. [3] 朱星成,王冬菊.降钙素原检测在感染性疾病中的临床应用[J].中国临床新医学,2016,9(2):128~132. [4] Ahsan Zil-E-Ali, Syeda Naqvi, Mariam Tariq. Procalcitonin: a powerful rescuer on surgical floors[J]. Cureus,2017,9(7):e1446. [5] Uzzan B, Cohen R, Nicolas P, et al.Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis[J]. CritCareMed,2006,34:1996~2003. [6] Lu J, Yu Y, Zhu I, et al. Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis[J]. Proc Natl Acad Sci U S A,2014,111(14):5189~5194. [7] Wang Y, Huang H, Sun R, et al. Serum amyloid a induces M2b-like macrophage polarization during liver inflammation[J].Oncotarget, 2017,8(65):109238~109246. [8] Pepys MB, Hirschfield GM. C-reactive protein: a critical update[J].Clin Invest, 2003, 111(12):1805~1812.
2018, Vol. 24 
冀公网安备13080202000786号