Abstract：Objective:To investigate the clinical effect of transnasal endoscopic resection of pituitary tumor with single nostrils. Methods:80 patients with pituitary tumor were enrolled from January 2014 to January 2017 were randomly divided into two groups. Endoscopic patients underwent endoscopic sinus surgery with a single nostrils. The clinical parameters, short-term prognosis, hormone level, postoperative complications and quality of life were compared between the two groups. Results: The intraoperative blood loss, operation time and hospitalization time were significantly lower in the endoscopic group than in the microscope group. The levels of GH, PRL and ACTH were significantly lower than those of the microscope group. The overall complication rate was significant (P<0.01). The difference of body function, body pain, overall health, vitality and quality of life between the two groups was significantly higher than that of the microscopic group (P<0.01). Conclusion: Compared with the microscope, the clinical effect of pituitary tumor resection under nasal transsphenoidal approach is more significant, less complication and higher quality of life in patients with endoscopic sinus surgery.
2018, Vol. 24 
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