Abstract：Objective: To investigate the clinical efficacy of Tongnao Decoction in the treatment of acute cerebral infarction (ACI) and its effect on blood circulation in patients with this disease. Methods: The randomized method was used to divide the 100 patients admitted into the group into two groups. The control group selected western medicine for routine symptomatic treatment, and the observation group took Tongnao Decoction on the basis of western medicine for routine symptomatic treatment. The changes of hemodynamics ηb, HCT, Fib, PAG, MST, serum D-D and VEGF were measured before and after treatment. The change of cerebral hemodynamic parameters MPV, DBFV, MBF, VPI and RI before and 3 months after treatment were compared between the two groups. The NHISS scores were compared between the two groups. The clinical efficacy of the two groups was statistically analyzed. Results: The cure rate (54.00%) and total effective rate (94.00%) in the observation group were significantly higher than those in the control group (30.00% and 78.00% respectively). The difference between the two groups was statistically significant (P<0.05). Analysis of variance of two-factor repeated measures showed that there were statistically significant differences in ηb, HCT, Fib, PAG, MST, MPV, DBFV, MBF, VPI and RI before and after treatment (P<0.05); There was significant difference between the control group and the observation group in ηb, HCT, Fib, PAG, MST, MPV, DBFV, MBF, VPI and RI (P<0.05). Conclusion: Tongnaoyin treatment of ACI, can effectively reduce blood viscosity, improve hemodynamics, accelerate blood circulation of brain tissue, promote the repair of nerve function in patients, the curative effect is definite.
2018, Vol. 24 
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