Abstract：Objective: To study the application of low temperature plasma tonsillectomy in children with obstructive sleep apnea hypopnea syndrome (OSAHS) and the effect on serum immunoglobulin and T lymphocyte subsets. Methods: 88 cases of children with OSAHS from September 2016 to August 2017 were selected in our hospital. All the children were divided into observation group and control group according to random number method. The control group was treated with the traditional tonsillectomy, and the observation group was given low-temperature plasma tonsillectomy. Two groups of patients with intraoperative and postoperative situation, as well as postoperative pain were analyzed, the levels of serum immunoglobulins and T lymphocyte subsets were compared between the two groups before and after 1 month of treatment. Results: The blood loss, operation time and length of hospital stay in the observation group were significantly shorter than the control group (P<0.05), but the time of alopecia in the observation group was longer than the control group (P<0.05). On the 1st, 3rd, 5th and 7th day postoperatively, the pain scores of the observation group were significantly lower than the control group (P<0.05). The levels of IgA, IgG and IgM immunoglobulins in the two groups were not significantly different (P> 0.05). After one month of treatment, IgA, IgG and IgM immunoglobulin levels in the control group were significantly higher than before treatment, IgM, IgG and IgM immunoglobulins in the observation group were not significantly different compared with before treatment (P<0.05). The levels of IgA, IgG and IgM immunoglobulins in the observation group were significantly higher than the control group (P<0.05). There was no significant difference in the percentage of CD3 +, CD4 +, CD8 + and CD4 + / CD8 + between the two groups before treatment (P> 0.05). After one month of treatment, the ratio of CD3 +, CD4 +, CD4 + / CD8 + CD8 + and CD4 + / CD8 + ratio in the treatment group were significantly lower than those before treatment (P<0.05), but there was no significant difference in CD3 +, CD4 +, CD8 + (P<0.05). The percentage of CD8 +, CD8 + and CD4 + / CD8 + in observation group were significantly higher than control group (P<0.05). Conclusion: Low temperature plasma tonsillectomy in children with OSAHS does not affect serum immunoglobulin and T lymphocyte subsets, less intraoperative bleeding, operation time and hospital stay, postoperative pain is less.
代红英,林勇. 低温等离子扁桃体切除术在OSAHS患儿中的应用及对血清免疫球蛋白与T淋巴细胞亚群的影响[J]. 河北医学, 2018, 24(10): 1589-1593.
DAI Hongying, LIN Yong. Application of Low Temperature Plasma Tonsillectomy in Children with OSAHS and its Influence on Serum Immunoglobulins and T Lymphocyte Subsets. HeBei Med, 2018, 24(10): 1589-1593.
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2018, Vol. 24 
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