Abstract：Objective: To analyze and discuss the effect of 308 nm excimer light on vitiligo. Methods: 250 patients with vitiligo admitted to our hospital from May 2013 to May 2018 were randomly divided into control group and experimental group according to random number table method. The patients in the control group were treated with 311 nm narrow-band ultraviolet radiation, while the experimental group was treated with 308 nm excimer light. The patients of two groups were treated twice a week, 30 times a week. The clinical efficacy of the two groups was evaluated. Results: After 3 courses of treatment, the effective rate of the control group was 46.40%, which was significantly lower than 57.60% of the experimental group (χ2=8.834, P<0.05). The average number of times of treatment was (9.24±4.11), significantly lower than that of the control group (12.37±3.94) (t=2.123, P<0.05). In the experimental group, the mean cumulative dose of efficacy was (7.38±4.72) J/cm2, significantly lower than that in the control group (29.88±8.56) J/cm2 (t=3.293, P<0.05). Conclusion: For vitiligo patients, 308 nm excimer phototherapy is more effective than 311 nm narrow-band ultraviolet irradiation, and the onset time is faster, which is worthy of clinical application.
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2019, Vol. 25 
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