Abstract：Objective: To evaluate the clinical effects of single and bilateral percutaneous vertebroplasty (PVP) in the treatment of senile vertebral compression fractures. Methods: 386 elderly patients with lumbar vertebral compression fractures who received PVP treatment in our hospital from Jun. 2016 to Feb. 2018 were divided into unilateral group(n=230, unilateral approach PVP treatment) and bilateral group(n=156, bilateral approach to PVP treatment), the curative effect and prognosis of the 2 groups were reviewed and analyzed. Results: Unilateral group operation and X-ray irradiation time were shorter than bilateral group, bone cement injection less than bilateral group (t=29.128、29.676、57.365,P<0.05),VAS score of 6 and 12 months after operation was significantly lower than that of bilateral group (t=19.851、45.307, P<0.05); The Cobb angle, vertebral height and ODI of the 2 groups were significantly improved after operation, but there was no significant difference between the groups (P>0.05); The QUALEFFO score of the unilateral group at 6 and 12 months after operation was significantly higher than that of the bilateral group (t=8.116、12.226, P<0.05); After treatment, the incidence of complications in unilateral group and bilateral group was 20% and 50.64% respectively. The incidence of unilateral group was significantly lower than that of bilateral group (χ2=39.856, P<0.05), The satisfaction degree of patients in unilateral group was 96.52%, which was significantly higher than 80.13% in bilateral group (χ2=27.503,P<0.05). Conclusion: The single and bilateral pedicle approach PVP can provide good results for the treatment of lumbar vertebral compression fractures in the elderly, but unilateral approach can achieve better results in relieving pain and improving the quality of life.
2019, Vol. 25 
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