Abstract：Objective: To explore the efficacy of intermittent theta burst stimulation (iTBS) combined with core muscle training in patients with post-stroke hemiplegia. Methods: A total of 79 patients with post-stroke hemiplegia treated at our hospital from February 2022 to February 2024 were retrospectively analyzed and divided into two groups based on treatment Methods the control group (n=41, routine treatment combined with core muscle training) and the combined group (n=38, iTBS added to the control group’s treatment). Both groups were treated for 2 weeks. Neurological function indicators [brain-derived neurotrophic factor (BDNF), neuron-specific enolase (NSE)], Berg Balance Scale (BBS) scores, motor ability (Fugl-Meyer scale), and stroke-specific quality of life (SS-QOL) scores were compared before and after treatment. Results: Before treatment, there were no significant differences in neurological function indicators, BBS scores, Fugl-Meyer scores, or SS-QOL scores between the two groups (P>0.05). After treatment, the combined group showed greater increases in BDNF levels, BBS scores, Fugl-Meyer scores, and SS-QOL scores, as well as a greater decrease in NSE levels compared to the control group (all P<0.05). Conclusion: The combination of iTBS and core muscle training demonstrates significant efficacy in patients with post-stroke hemiplegia, promoting neurological recovery, improving balance, enhancing motor ability, and significantly improving quality of life. This approach holds valuable clinical application potential.
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2025, Vol. 31 
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