Abstract:Objective: To investigate the efficacy and postoperative complications of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PVP) under the localization of computed tomography (CT) in the treatment of osteoporotic thoracolumbar compression fractures. Methods: The clinical data of 98 patients with osteoporotic thoracolumbar compression fracture admitted to our hospital from February 2020 to June 2021 were retrospectively analyzed. According to different surgical methods, they were divided into PVP group (47 cases) and PKP group (51 cases). The general operation conditions of the two groups, the vertebral height, Cobb angle, visual analog scale (VAS) and Barthel index evaluation scale of the two groups were compared before and 3 days after operation, and the complications of the two groups were observed. Result: The operative time, hospital stay and bone cement injection amount in PVP group were lower than those in PKP group, P<0.05; 3 days after operation, the vertebral body height of both groups increased and PKP group was higher than PVP group, Cobb Angle of both groups decreased and PKP group was lower than PVP group; preoperative and postoperative 3d vertebral height and Cobb Angle difference in PKP group were higher than those in PVP group (P<0.05). 3 days after surgery, VAS scores of both groups decreased and PKP group was lower than PVP group, Barthel index scores of both groups increased and PKP group was higher than PVP group; the difference values of 3dVAS score and Barthel index score in PKP group before and after surgery were higher than those in PVP group, P<0.05; the total complication rate of PKP group was 7.84% lower than that of PVP group 17.02%, P>0.05. Conclusion: Both CT-guided PKP and PVP have ideal effects and high safety in the treatment of osteoporotic thoracolumbar compression fractures. However, compared with CT-guided PVP, CT-guided PKP can improve the patient's vertebral body condition and reduce pain, which is worthy of clinical reference.