Abstract：Objective: To investigate the effect of bronchoalveolar lavage combined with immunoglobulin on the prognosis and imaging performance of children with severe mycoplasma pneumonia. Methods: One hundred and fifty children with SMPP admitted from January 2018 to December 2019 were selected as study subjects,and the children were divided into hormone group,propecia group,and combined treatment group according to the random number table method,with 50 cases in each group.In the hormone group,there were 28 males and 22 females,aged 5-12 years,mean age (8.62±1.03) years,duration of illness 7-14 days,mean (10.17±1.33) days; in the propecia group,there were 30 males and 20 females,aged 6-12 years,mean age (9.14±1.04) years,duration of illness 7-14 days,mean (10.22±1.28) days; in the combination therapy group,there were 26 males and 24 females,mean age (9.14±1.04) years,duration of illness 7-14 days,mean (10.22±1.28) days.group,26 males and 24 females,age 5-12 years,mean age (9.17±1.17) years,duration of disease 7-14 days,mean (9.44±1.19) days.In the hormone group,methylprednisolone 1~2mg/kg-d was administered intravenously for 5 days,and basic treatment such as anti-infection and appropriate rehydration was also given.The C-ball group was treated with immunoglobulin 400mg/kg-d intravenously for 5 days.In the combined treatment group,bronchoalveolar lavage was added on top of the treatment in the propofol group.The efficacy of the three groups and the imaging changes before and after treatment were observed. Results: The total effective rate of clinical treatment was 86.00% in the hormone group,84.00% in the propofol group,and 96.00% in the combined treatment group.The difference between the combined treatment group and the hormone and propofol groups was statistically significant (χ2=5.137,4.726,P=0.032,0.011).The results of the review of imaging after one week of treatment in the three groups showed that 16 cases (32.00%) of significant absorption in the hormone group and 18 cases (36.00%) of significant absorption in the propofol group were significantly lower than 22 cases (44.00%) in the combined treatment group,and the difference was statistically significant (P<0.05); 6 cases (12.00%) of bronchial occlusion in the hormone group and 8 cases (12.00%) of bronchial occlusion in the propofol group were statistically significant.The differences were statistically significant (P<0.05) when comparing 8 cases (16.00%) of bronchial occlusion in the hormone group (12.00%) and 8 cases (8.00%) in the propofol group with 4 cases (8.00%) in the combined treatment group. Conclusion: Bronchoalveolar lavage combined with immunoglobulin can effectively improve the treatment efficiency of children with severe mycoplasma pneumonia and promote the absorption of lung imaging lesions in children,which is worthy of clinical promotion.
鲁伟, 张微, 郑祝龄. 支气管肺泡灌洗术联合免疫球蛋白对重症支原体肺炎患儿预后及影像学表现的影响分析[J]. 河北医学, 2023, 29(7): 1222-1225.
LU Wei, et al. Effect of Bronchoalveolar Lavage Combined with Immunoglobulin on the Prognosis and Imaging Performance of Children with Severe Mycoplasma Pneumonia. HeBei Med, 2023, 29(7): 1222-1225.
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2023, Vol. 29 
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