Abstract:Objective: To investigate the pathogen distribution,imaging characteristics and related factors of respiratory failure in elderly patients with COPD complicated with community acquired pneumonia. Methods: A total of 154 patients with COPD complicated with community acquired pneumonia who were treated were selected as the observation group,while 154 patients with simple COPD were selected as the control group,the differences in pathogenic bacteria and imaging characteristics between the two groups were compared,and the differences in clinical data between the observation group and patients without respiratory failure were analyzed. Results: 93 strains of pathogenic bacteria were detected in the observation group,including Klebsiella pneumoniae,Escherichia coli,Streptococcus pneumoniae and atypical pathogens,accounting for 16.13%,13.98%,12.90% and 12.90% respectively.The proportion of lamellar infiltration shadow,consolidation shadow and cavity in the observation group was 86.36%,20.78% and 14.94% respectively,which was significantly higher than that in the control group (P<0.05).The proportion of ≥ 70 years old,APACHE Ⅱ score>15,serum albumin<30g/L,COPD course>10 years in patients with combined respiratory failure was 72.86%,65.71%,64.29% and 72.86%,(P<0.05).Logistic showed that age,APACHE Ⅱ,serum albumin and COPD course were the influencing factors of respiratory failure (P<0.05). Conclusion: Patients with COPD complicated by community-acquired pneumonia have a high rate of Klebsiella pneumoniae infection,with significant differences in imaging features between the two; the development of respiratory failure in patients with COPD complicated by community-acquired pneumonia is influenced by factors such as patient age and APACHE Ⅱ score.