无痛胃肠镜患者丙泊酚复合舒芬太尼麻醉效果及麻醉复苏情况分析

doi:10.3969/j.issn.1006-6233.2023.05.034

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (1155 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要 目的:探讨丙泊酚复合舒芬太尼对无痛胃肠镜患者麻醉效果和麻醉复苏的影响。方法:选取本院2020年3月至2021年11月138例择期行无痛胃肠镜患者,通过随机数字表法简单随机分为观察组和对照组,每组69例患者,观察组应用丙泊酚复合舒芬太尼,对照组应用丙泊酚,比较两组血流动力学、药物用量、认知功能。结果:两组麻醉优良率比较(P>0.05);两组麻醉入睡后平均动脉压(MAP)、心率(HR)较麻醉前降低,在胃镜检查中、肠镜检查中MAP、HR水平又出现升高,但仍低于麻醉前(P<0.05);观察组胃镜、肠镜检查MAP、HR低于对照组(P<0.05);两组麻醉后血氧饱和度(SpO₂)水平比较(P>0.05);观察组较对照组丙泊酚药物用量,检查后恢复时间短(P<0.05);观察组检查后30min简易智力状态检测量表(MMSE)评分低于对照组(P<0.05);两组检查后1h、3h MMSE评分比较(P>0.05);两组不良反应发生率比较(P>0.05)。结论:无痛胃肠镜患者应用丙泊酚复合舒芬太尼,操作中血液循环稳定,丙泊酚药物用量减少,检查完成后麻醉恢复快。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词 ：无痛胃肠镜, 丙泊酚, 舒芬太尼, 麻醉效果, 麻醉复苏

Abstract：Objective: To investigate the effect of propofol compounded with sufentanil on anesthetic efficacy and anesthetic resuscitation in patients undergoing painless gastroenteroscopy. Methods: A total of 138 patients who were waiting to undergo painless gastroscopy in our hospital from March 2020 to November 2021 were selected and simply randomly divided into observation and control groups by random number table method, 69 patients in each group. The observation group was given propofol compounded with sufentanil and the control group was given propofol. The hemodynamics, drug dosage and cognitive function were compared between the two groups.Results: There was no significant difference in good rate of anesthesia between the two groups (P>0.05). After anesthesia, mean arterial pressure (MAP) and heart rate (HR) were lower than those before anesthesia in both groups. MAP and HR were increased during gastroscopy and endoscopy, still lower than those before anesthesia (P<0.05). During gastroscopy and endoscopy, MAP and HR were lower in observation group than control group (P<0.05). After anesthesia, there was no significant difference in blood oxygen saturation (SpO2) between the two groups (P>0.05). The dosage of propofol was smaller in observation group than control group, and recovery time after examination was shorter in observation group (P<0.05). At 30 min after examination, score of mini-mental state examination (MMSE) was lower in observation group than control group (P<0.05). There was no significant difference in MMSE scores between the two groups at 1h and 3h after after examination (P>0.05). The difference in incidence of adverse reactions between the two groups was not statistically significant (P>0.05). Conclusion: The application of propofol compounded with sufentanil in patients undergoing painless gastroenteroscopy resulted in stable blood circulation during the operation, reduced dosage of propofol drug, and rapid recovery from anesthesia after completion of the examination.

Key words： Painless gastroenteroscopy Propofol Sufentanil Anesthesia effect Anesthesia resuscitation

基金资助:四川省卫生健康委员会科研课题,(编号:20PJ310)

引用本文:

刘文良, 余雪美, 熊朝晖. 无痛胃肠镜患者丙泊酚复合舒芬太尼麻醉效果及麻醉复苏情况分析[J]. 河北医学, 2023, 29(5): 872-876.
LIU Wenliang, et al. Analysis of the Effect of Propofol Compounded with Sufentanil Anesthesia and Anesthetic Resuscitation in Patients Undergoing Painless Gastroenteroscopy. HeBei Med, 2023, 29(5): 872-876.

链接本文:

http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2023.05.034 或 http://www.hbyxzzs.cn/CN/Y2023/V29/I5/872

[1] Jin R,Shi H,Liu H.Construction of narcotic drug management process in painless gastroenteroscopy under the principle of rationality,safety and standardization[J].Pharm Care Res,2020,20(6):469-471.
[2] 万幸,杨青青,樊迪,等.亚麻醉剂量艾司氯胺酮复合丙泊酚应用于无痛胃肠镜检查的效果[J].临床麻醉学杂志,2022,38(2):144-148.
[3] Li J,Li Y,Huang Z.Effect of dexmedetomidine on analgesia and sedation of sufentanil during anesthesia induction period of gynecological surgery[J].Pak Pharm Sci,2020,33(1):429-432.
[4] 庄心良,曾因明,陈佰銮.现代麻醉学[M].第3版.北京:人民卫生出版,2004.487-488.
[5] 岑伟.简易精神状态检查法与修订的长谷川痴呆量表的临床应用[J].神经病学与神经康复学杂志,2006,3(4):207-209.
[6] 余红春,江婷婷,贾洪峰.地佐辛与舒芬太尼复合丙泊酚在无痛肠镜麻醉中的应用效果比较[J].重庆医学,2020,49(14):2360-2362.
[7] Hao L,Hu X,Zhu B,et al.Clinical observation of the combined use of propofol and etomidate in painless gastroscopy[J].Medicine (Baltimore),2020,99(45):e23061.
[8] Kang S,Lu J,Zhou HM.Anesthetic strategy for obese patients during gastroscopy:deep sedation or conscious sedation,a prospective randomized controlled trial[J].Anesth,2021,35(4):555-562.
[9] Tu W,Yuan H,Zhang S,et al.Influence of anesthetic induction of propofol combined with esketamine on perioperative stress and inflammatory responses and postoperative cognition of elderly surgical patients[J].Am Transl Res,2021,13(3):1701-1709.
[10] 钟强,罗晓春,黄建成,等.丙泊酚复合舒芬太尼靶控输注对上腹部开腹手术患者苏醒质量的影响[J].中国医刊,2020,55(10):1154-1156.
[11] Allampati S,Wen S,Liu F,et al.Recovery of cognitive function after sedation with propofol for outpatient gastrointestinal endoscopy[J].Saudi Gastroenterol,2019,25(3):188-193.