Correlation Study between Vertebral CT Values and Bone Cement Leakage in Percutaneous Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures
GAO Zhichao, LI Zhe, XU Caiyuan, et al
Affiliated Hospital of Chengde Medical University, Hebei Chengde 067000, China
Abstract：Objective: To analyze the correlation between vertebral CT values and the occurrence of bone cement leakage in patients undergoing percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fractures (OVCF). Methods: A total of 61 patients with osteoporotic vertebral compression fractures admitted and treated with PVA at the Affiliated Hospital of Chengde Medical College between September 2019 and October 2022 were included. The patients were divided into the leakage group and non-leakage group based on whether bone cement leakage occurred. Patient demographics, including gender, age, intraoperative bone cement injection volume, fracture location (thoracic or lumbar), fracture compression degree, and CT values of the L1 vertebra, were recorded for both groups. Results: There were no statistically significant differences in gender, age, fracture location, and bone cement injection volume between the two groups (P>0.05). However, differences in fracture compression degree and CT values of the L1 vertebra were statistically significant (P<0.05). Multivariate logistic analysis revealed a statistically significant association between changes in L1 vertebra CT values and bone cement leakage (P<0.05). Further ROC curve analysis showed an area under the curve (AUC) of 0.674 (95% CI: 0.524~0.824, P=0.025). The optimal cutoff value for L1 vertebra CT values was 62.1 HU, with a sensitivity of 79.5% and specificity of 63.6%. Conclusion: Vertebral CT values of the L1 vertebra are correlated with bone cement leakage in PVA treatment for osteoporotic vertebral compression fractures. Preoperative measurement of L1 vertebra CT values has a certain guiding significance in evaluating bone cement leakage.
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2023, Vol. 29 
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