Abstract：Objective: To investigate the effect of two different pancreaticoenteric anastomotic techniques on postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy. Methods: A retrospective analysis of clinical data from patients undergoing pancreaticoduodenectomy at the Affiliated Hospital of Chengde Medical College from January 2020 to December 2022 was conducted. Patients were divided into two groups based on different pancreaticojejunostomy techniques: the "Chen's" pancreaticojejunostomy group (Chen's group, n=21) and the "Hong's one-stitch method" pancreaticojejunostomy group (Hong's group, n=44). The preoperative disease status, POPF, intraoperative bleeding, length of hospital stay, and hospitalization cost were compared between the two groups. Multivariate Logistic regression analysis was used to explore the effect of various indicators on the risk of complications such as pancreatic fistula. Results: There was no statistical significant difference in the size of pancreatic duct between the two groups (P>0.05). The preoperative bilirubin level and biliary drainage in Hong's group were higher than those in Chen's group (P<0.05). Intraoperative blood loss, length of hospital stay and hospitalization cost in Chen's group were lower than those in Hong's group (P<0.05). The POPF incidence in Chen's group was significantly lower than in Hong's group (56.82% vs 14.29%;χ2=10.49, P=0.001). Multivariate Logistic regression showed that there was no statistical significance in preoperative bilirubin level, biliary drainage, intraoperative blood loss, length of hospital stay and hospitalization cost between the two groups (P>0.05). Compared with Hong's group, Chen's group decease the incidence of POPF (P<0.05). Conclusion: Chen's pancreaticojejunostomy technique is associated with a lower risk of pancreatic fistula after pancreaticoduodenectomy, and it is worthy of clinical promotion and application.
陈琳光, 唐冠杰, 康庆民, 李剑. 不同胰肠吻合方式对胰十二指肠切除术后胰瘘的影响[J]. 河北医学, 2023, 29(11): 1886-1891.
CHEN Linguang, TANG Guanjie, KANG Qingmin, et al. The Effect of Different Pancreaticoenteric Anastomotic Techniques on Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy. HeBei Med, 2023, 29(11): 1886-1891.
2023, Vol. 29 
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