Abstract：Objective: To analyze the correlation between Red Blood Cell Distribution Width (RDW),high-sensitivity C-reactive protein (hs-CRP),and coagulation-fibrinolysis index with cerebral artery stenosis in patients suffering from ischemic stroke. Methods: A total of 126 patients with cerebral arterial thrombosis admitted to our hospital between January 2019 and May 2021 were included.They were categorized into two groups:the cerebral arterial stenosis group (n=57) and the cerebral arterial normal group (n=69) based on the presence of cerebral artery stenosis.Comparative analysis of RDW,high-sensitivity C-reactive protein (hs-CRP),and coagulation-fibrinolysis index was performed between the two groups,and their correlations were examined. Results: Significant differences were observed in the history of hypertension between the two groups of patients (P<0.05).In the cerebral arterial stenosis group,patients exhibited significantly larger red blood cell distribution width (RDW) values in the neck region compared to the cerebral arterial normal group (P<0.05).Additionally,hs-CRP levels in the cerebral arterial stenosis group were notably higher than those in the cerebral arterial normal group,with statistically significant differences (P<0.05).Furthermore,patients in the cerebral arterial stenosis group had significantly lower levels of activated partial thromboplastin time (APTT) compared to patients in the cerebral arterial normal group (P<0.05).In contrast,fibrinogen (FIB) and D-dimer (D-D) levels in the cerebral arterial stenosis group were significantly higher than those in the cerebral arterial normal group (P<0.05).Pearson or spearman correlation analysis results demonstrated a significant positive correlation between RDW,FIB,D-D,hs-CRP,and cerebral artery stenosis (P<0.05).However,APTT showed a significant negative correlation with cerebral artery stenosis (P<0.05). Conclusion: The findings suggest that RDW,hs-CRP,and coagulation-fibrinolysis index are indeed correlated with cerebral artery stenosis in patients with cerebral arterial thrombosis.
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2023, Vol. 29 
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