Correlation between Noninvasive Cardiac Function Assessment Indexes and NYHA Classification in Patients with Acute Exacerbation of Chronic Heart Failure
ZHANGjinlong, GUOjingtao, SUNnina, et al
The Second Clinical College of Chengde Medical University, Hebei Chengde 067000, China
Abstract：Objective: To investigate the correlation between noninvasive cardiac output (CO), cardiac index (CI), stroke volume (SV), left ventricular work (LCW), and NYHA cardiac function classification in patients with acute exacerbation of chronic heart failure (Chronicheartfailure, CHF). Methods: One hundred and forty-four patients with acute exacerbation of CHF admitted to the Department of Cardiology of Chengde City Central Hospital from November 2021 to October 2022 were selected and categorized into class IV (50 patients), class III (48 patients), and class II (46 patients) according to the cardiac function grading criteria of NYHA (American College of Cardiology). All patients underwent noninvasive hemodynamic cardiac function index testing and B-type natriuretic peptide (BNP) and cardiac ejection fraction (EF) testing, comparing the levels of CO, CI, SV, LCW, BNP, and EF in each group, and analyzing the correlation between CO, CI, SV, and LCW and the NYHA cardiac function classification of patients with acute exacerbation of CHF. Results: The values of CO, CI, SV, LCW, and EF in class Ⅱgroup were higher than those in class Ⅳgroup (P<0.05). The values of CO, CI, SV, LCW, and EF in class Ⅲ group were higher than those in class Ⅳ group (P<0.05). The values of CO, CI, SV, LCW, and EF in class Ⅱgroup were higher than those in the class Ⅲgroup. The BNP of the cardiac function class Ⅲ and Ⅳ groups was higher than that of the cardiac function class Ⅱgroup, but there was no significant difference in BNP between the cardiac function grade Ⅲ and Ⅳ groups (P>0.05). Spearman correlation analysis showed that CO, CI, SV, and LCW were negatively correlated with NYHA cardiac function grade in patients with acute exacerbation of CHF (r=-0.426, -0.368, -0.419, -0.348, P<0.05). Conclusion: As NYHA cardiac function classification worsened, CO, CI, SV, LCW, and EF values decreased, and noninvasive hemodynamic cardiac function assessment indexes were all negatively correlated with NYHA classification, and noninvasive hemodynamic cardiac function assessment indexes were helpful in guiding the assessment of cardiac function classification.
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2023, Vol. 29 
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