Abstract：Objective: To evaluate the diagnostic value of HRCT signs of pure ground glass nodules (pGGN) in non-lepidic invasive lung adenocarcinoma (IAC), and to find the optimal imaging indicator. Methods: The clinical data of 85 patients with IAC confirmed by surgical pathology and HRCT imaging data of 86 pGGNs were retrospectively analyzed. According to the pathology, they were divided into lepidic dominant group (48 cases, 47 patients) and non-lepidic dominant group (38 cases, 38 patients). The HRCT signs such as mean CT value, maximum diameter, burrs sign, abnormal vascular sign and abnormal bronchial sign were compared between the two groups. The ROC curve was analyzed with non-lepidic dominant adenocarcinoma as the dependent variable, and the area under the curve (AUC) was used to evaluate the diagnositic efficacy of each imaging indicator. Results: The mean CT value and maximum diameter of non-lepidic dominant IAC were higher than lepidic dominant IAC. The incidence of abnormal vascular sign, abnormal bronchial sign and burrs sign of non-lepidic dominant IAC was higher than lepidic dominant IAC (P<0.05). ROC curve analysis showed that the area under the curve of non-lepidic dominant IAC was 0.877,the efficiency was 0.895,the sensitivity was 0.729, and its diagnostic efficiency was higher than other indicators. Conclusion: The mean CT value has a high diagnositic value for non-lepidic dominant IAC with pGGN and is the optimal imaging indicator.
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2023, Vol. 29 
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