Abstract:Objective: To analyze and study the risk factors related to the severity of community-acquired pneumonia in children, in order to provide a basis for accurately determining the severity of the disease in children with community-acquired pneumonia, to provide early diagnosis and treatment of severe community-acquired pneumonia in children, and to minimise the mortality rate. Methods: Totally 494 children diagnosed with community-acquired pneumonia and hospitalized in our hospital from October 2020 to September 2021 were divided into 428 cases of general type and 66 cases of severe type according to the diagnostic criteria of severe community-acquired pneumonia. Their general conditions, symptoms and signs, laboratory indexes and imaging characteristics were studied retrospectively, and the clinical characteristics and influencing factors of the two groups were compared and studied. Results: Compared to the 428 children with general community-acquired pneumonia, the 66 children with severe community-acquired pneumonia were younger and had a higher proportion of signs and symptoms presenting with decreased breath sounds, tachycardia, extra-pulmonary complications, pleural effusion and lobar atelectasis; in laboratory tests, C-reactive protein (CRP), lactate dehydrogenase (LDH), creatine kinase isoenzyme (CK-MB) Logistic stepwise regression analysis showed that CRP and IL-6 were independent risk factors for severe community-acquired pneumonia in children. Conclusion: Elevated serum CRP and IL-10 levels have good accuracy in determining the severity of community-acquired pneumonia in children and help in the early identification of severe community-acquired pneumonia in children.
王丽, 于玉梅, 邓清秀, 封丽洁, 何双龙. 儿童社区获得性肺炎病情严重程度评价相关危险因素分析[J]. 河北医学, 2022, 28(5): 862-866.
WANG Li, YU Xiumei, DENG Qingxiu, et al. Analysis of Risk Factors Related to Severity Evaluation of Community-Acquired Pneumonia in Children. HeBei Med, 2022, 28(5): 862-866.