Abstract:Objective: To analyze the clinical features and high-risk factors of elderly type 2 diabetes mellitus (T2DM) with upper gastrointestinal hemorrhage. Methods: A total of 177 elderly patients with upper gastrointestinal hemorrhage were admitted to the hospital between May 2018 and May 2021, including 92 patients with T2DM (group A) and 85 patients without T2DM (group B). Meanwhile, 80 T2DM patients with healthy digestive tract were enrolled in this study as group C. The clinical features of group A and group B were compared. The clinical parameters of group B and group C were recorded, and the high-risk factors for elderly T2DM with upper gastrointestinal hemorrhage were analyzed.Results: There were statistically significant differences between group A and group B in terms of rhythmic abdominal pain, abdominal distension, bleeding site, and maximum diameter of ulcer (P<0.05). The response rate and Hp eradication rate in group A were lower than those in group B (P<0.05). Logistic regression analysis results showed that smoking history, drinking history, non-steroidal drug use, and Hp positive were risk factors of elderly T2DM with upper gastrointestinal hemorrhage (P<0.05).Conclusion: Elderly T2DM with UGIB have more gastric bleeding, larger gastric ulcers, and low Hp eradication rate. The risk of upper gastrointestinal hemorrhage is higher in elderly T2DM patients with smoking history, drinking history, non-steroidal drug use, and Hp-positive.
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