Clinical Efficacy of Transjugular Intrahepatic Portosystemic Shunt Combined with Functional Splenic Embolization in the Treatment of Portal Hypertension in Cirrhotic Decompensated Liver
DONG Yang, LIANG Guijie, et al
The Third Hospital of Chengde, Heibei Chengde 067000, China
Abstract：Objective: To study the clinical efficacy of transjugular intrahepatic portosystemic shunt (TIPS) combined with functional splenic embolization (FSE) in the treatment of portal hypertension in decompensated cirrhosis. Methods: A total of 100 patients with cirrhotic portal hypertension were randomly divided into control group and treatment group. In the control group, partial splenic artery embolization (PSE) was performed, while in the treatment group, transjugular intrahepatic portosystemic shunt (TIPS) and functional splenic embolization (FSE) were performed. The clinical efficacy of the two groups was evaluated after one intervention. The main observations were portal vein pressure, liver function, spleen volume, blood count, coagulation, recent survival and safety indicators in both groups. Results: After treatment, the portal vein pressure, liver function, spleen volume, blood routine and coagulation function in the treatment group were better than those in the control group (P<0.05); there was no statistical difference between the two groups in terms of recent survival and safety (P>0.05). Conclusion: Transjugular intrahepatic portosystemic shunt (TIPS) combined with functional splenic embolization (FSE) has a good clinical effect in the treatment of portal hypertension in cirrhotic decompensated liver, which is worthy of clinical promotion.
2022, Vol. 28 
冀公网安备13080202000677号