Abstract：Objective: To investigate the effect of simple tumor resection and partial pancreatectomy for insulinoma on the blood glucose level and prognosis of patients. Methods: 80 patients with insulinoma treated in our hospital from January 2017 to January 2020 were selected. According to different treatment methods, they were divided into resection group (43 cases, treated with simple tumor resection) and resection group (37 cases, treated with partial pancreatectomy). The changes of blood glucose level, prognosis and complications were compared between the two groups. Results: The FBG in the removal group was significantly higher at 1 day after surgery than before the operation (P<0.05), and the FBG at 30 days after surgery was significantly lower than before the operation (P<0.05), and the FBG in the resection group at 1d, 3, and 5 days after surgery FBG in the removal group was significantly lower than that in the resection group at 1d, 3d, 5d, and 7d after surgery (P<0.05). The FBG of the removal group was significantly lower than that of the resection group (P<0.05). There was no change in HbA1c in the two groups at 7d and 30d, and the HbA1c of the removal group was not statistically significant compared with the resection group (P>0.05). The average survival time of the removal group was significantly longer than that of the removal group (P<0.05). The incidence of short-term complications (27.91%vs21.62%) in the removal group was not statistically significant (P>0.05); the incidence of long-term complications (16.28%vs48.65%) in the removal group was significantly lower than the resection group (P<0.05). Conclusion: In the treatment of insulinomas of suitable size, the blood glucose level changes of simple tumor resection are less than that of partial pancreatectomy, the survival time of patients is relatively long, and the long-term complications after surgery are relatively fewer.
李冰, 周慧超, 王庆广. 单纯肿瘤摘除术和部分胰腺切除术治疗胰岛素瘤对患者血糖水平及预后的影响[J]. 河北医学, 2021, 27(7): 1219-1222.
LI Bing, ZHOU Huichao, WANG Qingguang. Effect of Pure Tumor Resection and Partial Pancreatectomy for Insulinoma on Blood Glucose Level and Prognosis. HeBei Med, 2021, 27(7): 1219-1222.
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2021, Vol. 27 
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