Abstract：Objective: To explore the changes in the standard uptake value (SUV) of positron emission computed tomography (PET-CT) in patients with colorectal cancer before surgery, and to analyze the diagnostic predictive value of PET-CT SUV for postoperative recurrence and metastasis of colorectal cancer. Methods: A total of 50 patients with colorectal cancer, from November 2017 to August 2020, who met the inclusion criteria in this study were included as observation subjects for retrospective study. The 50 patients underwent whole-body PET-CT examination before surgery, and the highest SUV (SUVmax) in the specific area of colorectal cancer lesions was calculated. In the follow-up the correlation between SUVmax and recurrence or metastasis was observed, and the diagnostic efficacy of SUVmax for colorectal cancer recurrence and metastasis was analyzed. Results: The median follow-up time was 23.5 months, and the follow-up rate was 100%. Of the 50 patients, 24 had local recurrence or metastasis, and 26 patients had no recurrence or metastasis. The preoperative SUVmax of patients with local recurrence or metastasis after operation was (5.3±2.3), and the preoperative SUVmax of patients without recurrence and metastasis after operation was (2.7±0.6). The preoperative SUVmax of the former was significantly higher than the latter, and the difference was statistically significant (t=4.587, P<0.05).When preoperative SUVmax=4.2, the diagnostic sensitivity and specificity of colorectal cancer recurrence and metastasis were 72.0% and 100.0% respectively, and the negative and positive predictive values were 73.0% and 100.0% respectively. Conclusion: The higher the preoperative SUVmax of colorectal cancer patients, the greater the chance of tumor recurrence and metastasis in the near future. The preoperative SUV has important value in predicting the recurrence and metastasis of colorectal cancer patients.
张将, 陈亚明, 王蒙, 刘相飞. PET-CT SUV值对结直肠癌患者术后复发与转移的诊断价值[J]. 河北医学, 2021, 27(6): 892-895.
ZHANG Jiang, CHEN Yaming, WANG Meng, et al. The Diagnostic Value of PET-CT SUV for Postoperative Recurrence and Metastasis of Colorectal Cancer. HeBei Med, 2021, 27(6): 892-895.
[1] 游金辉,黄霓.结直肠癌PET/CT显像的应用与研究进展[J].川北医学院学报,2019,34(1):155~159. [2] 丁重阳,李天女,孙晋.18F-FD G PET/CT 代谢参数与结直肠癌临床病理特征的关系[J].临床肿瘤学杂志,2017,22(1):53~57. [3] 马文波,刘胡.PET-CT/MRI融合图像诊断直肠癌淋巴结转移的价值分析[J].中国CT和MRI杂志,2020,18(3):42~44. [4] 高晶晶,李绍东,李江山,等.PET/CT-MRI三模式在直肠癌局部分期中的应用[J].中国医学计算机成像杂志,2017,23(2):185~190. [5] 王磊,蔡建,秦启元.结直肠癌腹膜转移治疗的争议与思考[J].中华外科杂志,2018,56(8):569~572. [6] 田蓉蓉,薄云峰,张毅勋,等.18F-FDG PET/CT显像与结直肠癌治疗前分期的相关性研究[J].国际放射医学核医学杂志,2018,42(1):9~14. [7] Zhang L,Sun H,Du S,et al.Evaluation of 18F-FDG PET/CT parame-ters for reflection of aggressiveness and prediction of prognosis inearly-stagecervicalcancer[J].NuclMed Commun,2018,39(11):1045 [8] Nakajo M,Kajiya Y,Tani A,et al.A pilot study for texture analysis of 18F-FDG and 18F-FLT-PET/CT to predict tumor recurrence of patients with colorectal cancer who received surgery[J].Eur Nucl Med Mol Imaging,2017,44(13):2158. [9] 丁重阳,李天女,郭喆,等.18氟-氟代脱氧葡萄糖PET/CT检查判断结直肠癌术后预后的临床价值[J].中华消化外科杂志,2016(10):1018.
2021, Vol. 27 
冀公网安备13080202000677号