Abstract：Objective: To investigate the high distribution of antibody titers in maternal-fetal ABO blood type incompatibility and its effect on the newborn with ABO blood type incompatible hemolytic disease. Methods: A retrospective analysis of 760 type O Rh-negative parturients (whose husbands are not type O Rh-negative) and their newborns is made to discuss the high distribution of antibody titers and the effect on hemolysis of newborns. Results: Among 760 pregnant women with ABO incompatibility, the titer increases with the increasing of gestational time and gestational age, and the difference is statistically significant. These pregnant women are sub-grouped according to their husbands' ABO blood type, and there is no significant difference in antibody titers between groups. With the increasing of antibody titer, the incidence of hemolytic disease in newborns is on the rise. Conclusion: Dynamic monitoring of maternal antibody titers during pregnancy is significant to reducing neonatal hemolytic disease caused by maternal-fetal ABO blood type incompatibility and can improve the quality of the birth population.
赵郡, 张蕾, 邢慧敏. 母婴血型不合对新生儿溶血病的影响[J]. 河北医学, 2021, 27(6): 1018-1021.
ZHAO Jun, ZHANG Lei, et al. An Analysis of the Effect of Maternal-Infant Blood l Group Incompatibility on Neonatal Hemolysis. HeBei Med, 2021, 27(6): 1018-1021.
2021, Vol. 27 
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