Abstract：Objective: To investigate the risk factors of upper gastrointestinal bleeding in patients with coronary heart disease after percutaneous coronary intervention (PCI). Methods: The data of 1960 patients with coronary heart disease admitted to our hospital from June 2015 to June 2019 and treated by PCI were retrospectively analyzed. In the follow-up of 1 year after surgery, the incidence of upper gastrointestinal bleeding was counted, patients with upper gastrointestinal bleeding were recorded as the occurrence group, and patients without upper gastrointestinal bleeding were recorded as the non-occurring group, the basic data of the two groups were compared, and the independent risk factors for upper gastrointestinal tract after PCI were determined by Logistic multivariate analysis. Results: In the follow-up of 1 year, a total of 20 cases of 1960 coronary heart disease patients after PCI had upper gastrointestinal bleeding, the incidence was 1.07%. Univariate analysis showed that there were no significant difference in the proportions of gender, smoking history, drinking history, comorbidities, time from onset of coronary heart disease to consultation, medication after PCI, diseased branches, location of the lesion, degree of stenosis , hemoglobin, and platelet count between the two groups (P>0.05) ), there were statistically significant differences in the proportions of age, past history of digestive tract disease, chronic renal insufficiency, history of acute myocardial infarction, PCI operation time and creatinine clearance (P<0.05). Logistic multivariate analysis showed that age > 60 years old, past history of digestive tract disease, chronic renal insufficiency, history of acute myocardial infarction, PCI operation time > 90 min and creatinine clearance ≤ 60 mL/min all affect the upper digestion of patients with coronary heart disease after PCI independent risk factors for tract bleeding. Conclusion: Patients with coronary heart disease after PCI are at risk of upper gastrointestinal bleeding, and older >60 years old, past gastrointestinal medical history, chronic renal insufficiency, history of acute myocardial infarction, PCI operation time> 90 min and creatinine clearance ≤ 60 mL/min are all independent risk factors affecting upper gastrointestinal bleeding in patients with coronary heart disease after PCI.
2021, Vol. 27 
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