Influence of Operation Combined with Corneal Limbal Stem Cell Autograft Transplantation on Visual Quality Corneal Diopter and Tear Film Function in Pterygium Patients
HUANG liumeng, XIE Shunong
The 909 Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Fujian Zhangzhou 363000, China
Abstract：Objective: To treat pterygium patients with pterygium excision combined with corneal limbal stem cell autograft transplantation, and to explore the effects on visual quality, corneal diopter and tear film function. Methods: A total of 120 pterygium patients who were treated in the hospital from September 2017 to December 2019 were enrolled as the research objects. They were divided into study group (n=60) and control group (n=60) by random number table method. The control group was treated with pterygium excision, while study group was treated with corneal limbal stem cell autograft transplantation after pterygium excision. Their effects on visual quality, corneal diopter and tear film function were analyzed. Results: After surgery, SR and IMTFcutoff were significantly increased, while TF-OS was decreased in both groups. SR and IMTFcutoff in study group were significantly higher than those in control group, while TF-OS was lower than that in control group (P<0.05). After surgery, UCVA, corneal vertical curvature and horizontal curvature were significantly increased, while CAD was decreased in both groups. UCVA, corneal vertical curvature and horizontal curvature in study group were significantly lower than those in control group, while CAD was higher than that in control group (P<0.05). After surgery, BUT and SIT were significantly increased in both groups, which were significantly higher in study group than control group (P<0.05). After surgery, scores of OSDI and CFS were significantly decreased in both groups, which were lower in study group than control group (P<0.05). After surgery, incidence of complications and recurrence rate in study group were 1.67% and 5.00%, which were significantly lower than those in control group (13.33%, 18.33%) (P<0.05). Conclusion: Pterygium excision combined with corneal limbal stem cell autograft transplantation in the treatment of pterygium can significantly improve corneal diopter, tear film function and visual quality, which can reduce damage to eye epithelial cells and postoperative recurrence rate, with better prognosis.
2021, Vol. 27 
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