Abstract:Objective: To analyze the curative effect of posterior short-segment combined with vertebral pedicle internal fixation for thoracolumbar burst fracture. Methods: 176 patients with thoracolumbar burst fractures admitted to the hospital from June 2016 to January 2018 were enrolled. Among them, 92 patients underwent posterior short-segment combined with vertebral pedicle internal fixation (observation group). 84 patients underwent long-segment pedicle fixation through posterior approach (control group). The perioperative indicators, score of visual analogue scale (VAS) of pain in back and loin, Oswestry dysfunction index (ODI), Frankel functional grading at the last follow-up, Cobb's angle and improvement of vertebral anterior edge height were compared between the two groups. The occurrence of adverse events was observed. Results: The operation time, intraoperative blood loss and postoperative hospital stay in observation group were significantly less than those in control group (P<0.05). At the last follow-up, there was no significant difference in the improvement of VAS score, ODI score or Frankel functional grading between the two groups (P>0.05), while the recovery of Cobb's angle and vertebral anterior edge height in observation group was significantly better than that in control group (P<0.05). There were no adverse events after operation in both groups. And there was no case with the failure of internal fixation. Conclusion: Posterior short-segment combined with vertebral pedicle internal fixation can effectively restore the height of the injured vertebrae in the treatment of thoracolumbar burst fracture and correct the kyphosis. The curative effect is better than that of long-segment pedicle fixation.