Abstract：Objective: To investigate the role of dexmeditomidine (Dex) in preventing agitation during the resuscitation period of sevoflurane anesthesia in children.Methods: 100 cases of pediatric laparoscopic hernia surgery with sevoflurane anesthesia from January 2018 to January 2019 in our hospital were selected and sub-grouped into Dex group (n = 50) and control group (n = 50) according to admission sequence of odd or even numbers. Normal saline and Dex pump were administered to both groups. Incidence of restlessness and awakening time were recorded. Results: The incidence of agitation in the Dex group was 4.0%, lower than that in the control group (26.0%), and the difference was statistically significant (P<0.05).The scores of agitation and pain in the Dex group were lower than those in the control group when they were just admitted to the recovery room, 5 min after entry, 10 min after entry, and Ramsay sedation scores at 1-3 h after extubation were higher than those in the control group (P<0.05).There was no statistically significant difference between the two groups in the time of anesthesia recovery and time to leave the recovery room (P>0.05). Conclusion: Dex can prevent the occurrence of sevoflurane agitation during the awaking period of anesthesia in children and ensure the safety of surgery.
王秋锋, 梁启胜, 程向阳, 蔡宁, 梁东锋. 右美托咪定预防小儿七氟醚麻醉苏醒期躁动的研究[J]. 河北医学, 2021, 27(4): 588-592.
WANG Qiufeng, et al. A Study on the Effect of Dexmedetomidine on the Agitation of Sevoflurane Anesthesia in Children. HeBei Med, 2021, 27(4): 588-592.
2021, Vol. 27 
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