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隐匿性乙型肝炎病毒感染的研究进展 |
王成伟, 咸建春 |
南通大学第五附属医院肝病科, 江苏 泰州 225300 |
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[1] 中华医学会感染病学分会,中华医学会肝病学分会.慢性乙型肝炎防治指南(2019年版)[J].中华传染病杂志,2019,37(12):711~736. [2] Mak Lung-Yi,Wong Danny Ka-Ho,Pollicino Teresa,et al. Occult hepatitis B infection and hepatocellular carcinoma:Epidemiology,virology,hepatocarcinogenesis and clinical significance[J] .Hepatol,2020,73:952~964. [3] Yip Terry Cheuk-Fung,Wong Grace Lai-Hung.Current knowledge of occult hepatitis B infection and clinical implications[J] .Semin. Liver Dis.,2019,39:249~260. [4] Candotti Daniel,Assennato Sonny Michael,Laperche Syria et al. Multiple HBV transfusion transmissions from undetected occult infections:revising the minimal infectious dose[J] .Gut,2019,68:313~321. [5] Zhu Hui-Lan,Li Xu,Li Jun et al. Genetic variation of occult hepatitis B virus infection[J] .World J. Gastroenterol,2016,22:3531~3546. [6] Loomba Rohit,Liang T Jake.Hepatitis B reactivation associated with immune suppressive and biological modifier therapies:current concepts,management strategies,and future directions[J] .Gastroenterology,2017,152:1297~1309. [7] Williams John Bradley,Hüppner Alena,Mulrooney-Cousins Patricia M,et al. Differential expression of woodchuck toll-like receptors 1-10 in distinct forms of infection and stages of hepatitis in experimental hepatitis B virus infection[J] .Front Microbiol,2018,9:3007. [8] Sadeghi A,Yahyapour Y,Poortahmasebi V et al. Clearance of HBV DNA in immunized children born to HBsAg-positive mothers,years after being diagnosed with occult HBV infection[J] .Viral Hepat,2016,23:282~285. [9] Lu Ying,Liu Ya-Lin,Nie Jing-Jing et al. Occult HBV infection in immunized neonates born to HBsAg-positive mothers: a prospective and follow-up study[J] .PLoS One,2016,11:e0166317. [10] Wong Danny Ka-Ho,Cheng Serene Ching Yan,Mak Loey Lung-Yi,et al. Among patients with undetectable hepatitis B surface antigen and hepatocellular carcinoma,a high proportion has integration of HBV DNA into hepatocyte DNA and no cirrhosis[J] .Clin Gastroenterol Hepatol,2020,18:449~456. [11] Saitta Carlo,Tripodi Gianluca,Barbera Adalberto et al. Hepatitis B virus (HBV) DNA integration in patients with occult HBV infection and hepatocellular carcinoma[J] .Liver Int,2015,35:2311~2317. [12] Yang Ruifeng,Song Guangjun,Guan Wenli et al. The Lumipulse G HBsAg-Quant assay for screening and quantification of the hepatitis B surface antigen[J] .Virol Methods,2016,228:39~47. [13] Ozeki Itaru,Nakajima Tomoaki,Suii Hirokazu et al. Analysis of hepatitis B surface antigen (HBsAg) using high-sensitivity HBsAg assays in hepatitis B virus carriers in whom HBsAg seroclearance was confirmed by conventional assays[J] .Hepatol Res,2018,48:E263~E274. [14] Zhang Kai,Liu Yan,Chen Rongjuan et al. Antigenicity reduction contributes mostly to poor detectability of HBsAg by hepatitis B virus (HBV) S-gene mutants isolated from individuals with occult HBV infection[J] .Med Virol,2018,90:263~270. [15] Cholongitas Evangelos,Haidich Anna-Bettina,Apostolidou-Kiouti Fani et al. Hepatitis B virus reactivation in HBsAg-negative,anti-HBc-positive patients receiving immunosuppressive therapy:a systematic review[J] .Ann Gastroenterol,2018,31:480~490. |
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