Abstract:Objective: To analyze and evaluate the clinical effect of different materials of computer aided design/manufacture (CAD/CAM) pulp superonlay in the restoration of tooth defect after root canal treatment. Methods: A total of 120 patients with dental defects after root canal treatment admitted to the Second Affiliated Hospital of Hainan Medical College from January 2019 to July 2020 were prospectively selected as the research subjects. They were simply randomly divided into two groups: group A (60 patients), who were treated with super inlays of Lava Ultimate nanocomposite porcelain, and group B (60 patients), who were treated with multilayer feldspar glass ceramics Vita TriLuxe. The clinical prosthetic efficacy of the two groups of patients 6 months after restoration and 12 months after restoration (including edge fit, shape, edge coloring, color matching, secondary caries, surface texture, food impaction, and antagonistic teeth Abrasion) and the patient’s satisfaction with the repair were compared and analyzed. Results: 6 months and 12 months after restoration, there was no statistically significant difference in the edge fit, shape, edge coloring, color matching, secondary caries, surface texture, and food impact ratio between group A and group B. (P>0.05), but the abrasion of jaw teeth in group A was significantly better than that in group B, and the difference was statistically significant (P<0.05). The satisfaction rate of patients in group A (96.67%) was significantly higher than that of group B (85.00%), the difference was statistically significant (χ2=4.092, P=0.043). Conclusion: There is no significant difference between Lava Ultimate nanocomposite porcelain and Vita TriLuxe TriLuxe multilayer color vitalite glass ceramics in the clinical efficacy of CAD/CAM pulp superonlay in the restoration of tooth defects after root canal treatment in the aspects of edge density, shape, edge coloring, color matching, secondary caries, surface texture and food inserts. However, Lava Ultimate nanocomposite porcelain has significantly lower tooth abrasion than Vita TriLuxe multilayer color feldspar glass ceramics, and significantly higher patient satisfaction rate, which is more worthy of promotion.