Abstract：Objective: To investigate the clinical effect of multistep continuous physiotherapy combined with anti-mite and anti-inflammation in the treatment of demodex blepharitis. Methods: The clinical data of 76 patients (152 eyes) with demodex blepharitis admitted from January 2018 to October 2020 were retrospectively analyzed. Patients were divided into groups A and B according to their different treatment methods. Group A was selected to complete physical mite removal and anti-inflammatory in the treatment at home by themselves(4- Turpentine alcohol wipes and Tobramycin dexamethasone eye cream). Group B was selected for the multistep continuous physiotherapy with the combination of anti-mite and anti-inflammation(4- Turpentine alcohol wipes and Tobramycin dexamethasone eye cream). Multistep continuous physiotherapy was conducted clinically. Patients were instructed to complete eyelid cleaning and anti-mite and anti-inflammatory at home. The symptoms and signs(under the slit lamp examination eyelid edge clean degree, meibomian gland abnormalities and conjunctival congestion situation) of the two groups were observed before and after treatment for 1 month and 3 months and the results of light microscope examination of demodex were recorded, and statistical analysis was performed. Results: Before the treatment, symptoms and signs of the two groups of patients were close, and there was no statistically significant difference (P>0.05). At the end of 1 month and 3 month, symptoms and signs scores decreased significantly in both groups, and the decrease was outstanding in group B. Compared with before treatment in both groups, the difference had statistical significance (P<0.05). After 3 months, scores comparison between the two groups was statistically significant (P<0.05). The effective treatment rate of group B was 84.2%, and that of group A was 42.1%, the difference was statistically significant (P<0.05). Treatment for 3 months, creep mite count in both groups was significantly decreased, the difference was statistically significant (P<0.05). The treating process shows no complications such as glucocorticoid-induced high intraocular pressure and allergic reactions. Conclusion: Multi-step continuous physical therapy combined with anti-mite and anti-inflammatory therapy can significantly improve the therapeutic efficiency of patients with demodex blepharitis and improve the patient's symptoms and signs, which can be used as a routine physical therapy.
胡晓娟, 任彦新, 李希炜, 梁四妥, 王亚莉, 张翠玉. 多步骤连续物理治疗联合除螨抗炎治疗蠕形螨睑缘炎临床疗效[J]. 河北医学, 2021, 27(12): 2018-2022.
HU Xiaojuan, et al. Clinical Effect of Multistep Continuous Physiotherapy Combined with Anti-Mite and Anti-Inflammation in the Treatment of Demodex Blepharitis. HeBei Med, 2021, 27(12): 2018-2022.
2021, Vol. 27 
冀公网安备13080202000677号