Abstract：Objective: To explore the effect of Enhanced External Counterpulsation(EECP) on the cardiac function and prognosis of chronic total occlusion (CTO) patients with reduced ejection fraction. Methods: A total of 220 CTO inpatients with EECP therapy and a control group of 220 cases without EECP, which were consecutively enrolled from January 2015 to January 2019 in the division of cardiology in our hospital. The clinical data of the patients were collected and analysis. Results: There were not significant difference in smoking, hypertension and type 2 diabetes between two groups (all P>0.05). Compared to control group, left ventricular ejection fraction,6-minute walk test(6MWT) and B-type natriuretic peptide(BNP) were significantly higher in EECP group after therapy (all P<0.05). In addition, Point-biserial correlation analysis found that EECP was associated with 6MWT and BNP, which correlation coefficient were 0.454 and -0.523. Besides, the multivariate COX regression model showed that EECP was an independent protect prognostic risk factors of CTO with reduced ejection fraction and HR was 0.357(P<0.05). Conclusion: EECP therapy can improve exercise tolerance and cardiac function, which was an independent protect prognostic risk factors of CTO with reduced ejection fraction undergone PCI.
张海娟, 石秀彩, 马妹花, 邵丽莉. 440例冠状动脉慢性完全闭塞病变伴心功能不全患者应用增强型体外反搏治疗的远期预后[J]. 河北医学, 2021, 27(11): 1871-1877.
ZHANG Haijuan, SHI Xiucai, MA Meihua, et al. Outcome of 440 Chronic Total Occlusion and Left Ventricular Dysfunction Patients with or Without Enhanced External Counterpulsation. HeBei Med, 2021, 27(11): 1871-1877.
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2021, Vol. 27 
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