Abstract：Objective: To explore the application value of ultrasound elastography strain rate ratio (SR) and multi-slice spiral computed tomography (MSCT) in the diagnosis of thyroid nodules. Methods: The clinical data of 208 patients with thyroid nodules in our hospital from January 2016 to June 2019 were retrospectively analyzed. The differences between MSCT and surgical pathology (gold standard) in the diagnosis of benign and malignant thyroid nodules were compared. Receiver operating characteristic curve (ROC curve) was used to obtain the optimal threshold of ultrasound elastography SR in the diagnosis of malignant thyroid nodules. 208 patients with thyroid nodules were given diagnosis. The diagnostic value of MSCT and ultrasound elastography SR on thyroid nodules was analyzed. Results: Among 292 nodules in 208 patients with thyroid nodules, there were 193 benign nodules and 99 malignant nodules. A total of 237 (81.16%) nodules were accurately diagnosed by MSCT, and the Kappa value was 0.599, with moderate consistency. The ultrasound elastography SR value of malignant thyroid nodules was significantly higher than that of benign thyroid nodules, the difference was statistically significant (P<0.05). After ROC curve analysis, ultrasound elastography SR had a high diagnostic value on malignant thyroid nodules, the difference was statistically significant (AUC=0.956, P<0.05), and its optimal threshold was 2.978 in the diagnosis of malignant thyroid nodules. 266 (91.10%) nodules were accurately diagnosed by the optimal threshold of ultrasound elastography SR, and Kappa value was 0.806, with extremely strong consistency. The sensitivity, specificity, positive predictive rate, negative predictive rate and accuracy rate of MSCT for thyroid nodules were lower than those of ultrasound elastography SR, the difference was statistically significant (P<0.05). Conclusion: Ultrasound elastography SR has higher accuracy rate than MSCT in the qualitative diagnosis of thyroid nodules, and has higher clinical application value.
聂云雷, 侯庆玲, 张呈祥. 超声弹性成像应变率比值法与MSCT在诊断甲状腺结节中的应用[J]. 河北医学, 2021, 27(1): 128-130.
NIE Yunlei, HOU Qingling, ZHANG Chengxiang. Application of Ultrasound Elastography Strain Rate Ratio Method and MSCT in the Diagnosis of Thyroid Nodules. HeBei Med, 2021, 27(1): 128-130.
2021, Vol. 27 
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