Abstract：Objective: To evaluate the application effects of pectoralis major myocutaneous flap and free anterolateral femoral flap in defect repairing after oral cancer surgery.Methods: The clinical data of 90 patients with oral cancer from June 2016 to June 2019 were retrospectively analyzed.They were catagorized into pectoralis major group (34 cases) and anterolateral femoral group (56 cases) according to the different transplanted flaps.Tumor enlargement resection+cervical lymph node dissection were performed on all patients, and pectoralis major myocutaneous flap was used to repair the defects in pectoralis major group, and free anterolateral femoral flap was used to repair the defects in anterolateral femoral group.The perioperative indicators, occurrence of vascular crisis, flap survival and occurrence of postoperative complications were recorded in the two groups.The quality of life of the patients before surgery and 6 months after surgery was evaluated with University of Washington Quality of Life Questionnaire (UW-QOL).Results: There were no significant differences in flap area and postoperative drainage volume between the two groups (P>0.05), and the flap preparation time and defect repairing time in pectoralis major group were significantly shorter than those in anterolateral femoral group (P<0.05).The incidence rate of vascular crisis and overall flap survival rate were 11.76% and 91.18% in pectoralis major group, which were not statistically different from 12.50% and 91.07% in anterolateral femoral group (P>0.05).The total incidence rate of postoperative complications in pectoralis major group was significantly higher than that in anterolateral femoral group (23.53% vs 7.14%) (P<0.05).At 6 months after surgery, the UW-QOL scores in the two groups were higher than those before surgery, but there was no significant difference in the increase between the two groups (P>0.05).Conclusion: Pectoralis major myocutaneous flap and free anterolateral femoral flap have high flap survival rate in defect repairing after oral cancer surgery, and they can effectively improve the quality of life, but free anterolateral femoral flap can reduce the risk of postoperative complications.
刘法鑫, 黄磊, 白植宝. 胸大肌皮瓣与股前外侧游离组织皮瓣在口腔癌手术缺损修复中的应用[J]. 河北医学, 2020, 26(9): 1556-1561.
LIU Faxin, HUANG Lei, BAI Zhibao. Application Study of Pectoralis Major Myocutaneous Flap and Free Anterolateral Femoral Flap in Defect Repairing After Oral Cancer Operation. HeBei Med, 2020, 26(9): 1556-1561.
2020, Vol. 26 
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