The Curative Effect of Early Interventional Embolization on the Treatment of Intracranial Aneurysm and Its Effect on the Patients' Neurological Function Mental State and Activities of Daily Living
LI Jiangtao, YANG Hua, FAN Yujun
The First People's Hospital of Guangyuan, Sichuan Guangyuan 628000, China
Abstract：Objective: To explore the therapeutic effect of early interventional embolization in the treatment of intracranial aneurysms, and to observe the effects of early interventional embolization on the neurological function, mental state and activities of daily living of the patients. Methods: The patients with intracranial aneurysm (n=84) from March 2016 to March 2019 were selected as experimental subjects, and divided into two groups with the random digital table method. The control group (n=42) was treated with advanced interventional embolization, and the observation group (n=42) was treated with early intervention. The clinical effect, complication rate, prognosis, neurological function score (NIHSS), daily life ability score (ADL) and mental state score (KPS) were observed before and after treatment. Results: The total effective rate of the observation group was 95.24% in comparison with 71.43% of the total effective rate of the control group(χ2=8.571, P<0.05).Compared with 14.29% of the mortality rate and 23.81% of the disability rate in the control group, the mortality rate in the observation group was 2.38% and the disability rate was 4.76% The difference between the two groups was obvious and statistically significant(P<0.05). The results of repeated ANOVA showed that the NHISS score, KPS score, ADL score, intra-subject effect and inter-subject effect of different time points were statistically significant(P<0.05).The NHISS score of the patients in the observation group was (14.50±1.81), which was significantly lower than that in the control group [(20.19±4.24), P<0.05].The scores of KPS (86.05±6.84) were higher than that in the control group[(78.36±7.58), P<0.05]. The score of ADL (78.45±7.62) was significantly higher than that in the control group[(61.57±8.06), P<0.05], and the MMSE score (26.52±4.17) was significantly higher than that in the control group[(19.86±4.71), P<0.05].Compared with 26.19% of the total complications in the control group, the total incidence of complications in the observation group was 7.14%. There was significant difference between the two groups(χ2=5.486, P<0.05). Conclusion: Compared with advanced interventional embolism, early interventional embolism has a better effect on intracranial aneurysm, which can significantly improve the neurological status of patients, improve the ability of daily living, restore neurological function, effectively reduce complications, and the prognosis of patients is good.
李江涛, 杨华, 范玉军. 早期介入栓塞治疗颅内动脉瘤的效果及对患者神经功能精神状态和日常生活能力的影响[J]. 河北医学, 2020, 26(8): 1317-1320.
LI Jiangtao, YANG Hua, FAN Yujun. The Curative Effect of Early Interventional Embolization on the Treatment of Intracranial Aneurysm and Its Effect on the Patients' Neurological Function Mental State and Activities of Daily Living. HeBei Med, 2020, 26(8): 1317-1320.
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2020, Vol. 26 
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