Abstract:Objective: To investigate the diagnostic value of carotid ultrasound (CAU) combined with transcranial doppler (TCD) to obtain hemodynamic parameters for H-type hypertension. Methods: 108 patients with H-type hypertension (observation group) and 124 patients with simple hypertension (control group) were selected. The average blood flow velocity (Vm), resistance index (RI) and pulsation index (PI) of common carotid artery, middle cerebral artery and vertebral artery were obtained by CAU and TCD.To analyze the value of hemodynamic parameters obtained by CAU combined with TCD in the diagnosis of H-type hypertension. Results: Vm of common carotid artery, middle cerebral artery and vertebral artery in the observation group was lower than that in the control group (P<0.05), RI and PI were higher than those in the control group (P<0.05).Multivariate logistic regression analysis showed that common carotid artery RI and middle cerebral artery RI were independently correlated with type H hypertension (P<0.001).The area under curve (AUC) of common carotid artery RI, middle cerebral artery RI and common carotid artery RI combined with middle cerebral artery RI in diagnosing H-type hypertension was 0.770, 0.677 and 0.850, respectively. Conclusion: Hemodynamic abnormalities in patients with H-type hypertension are more obvious than those in patients with simple hypertension. The hemodynamic parameters obtained by CAU combined with TCD have higher diagnostic value for H-type hypertension.
黄海芬, 李韧, 张文龙. 血流动力学参数评价颈动脉超声联合TCD对H型高血压的诊断价值[J]. 河北医学, 2020, 26(4): 558-563.
HUANG Haifen, LI Ren, ZHANG Wenlong. Evaluation of Diagnostic Value of Carotid Ultrasound Combined with TCD in H-type Hypertension Based on Hemodynamic Parameters. HeBei Med, 2020, 26(4): 558-563.
[1] 李建平,卢新政,霍勇,等.H型高血压诊断与治疗专家共识[J].中华高血压杂志,2016,24(2):123~127. [2] Chen Z,Wang F,Zheng Y,et al.H-type hypertension is an important risk factor of carotid atherosclerotic plaques[J].Clin Exp Hypertens,2016,38(5):424~428. [3] Scoutt LM,Gunabushanam G.Carotid Ultrasound[J].Radiol Clin North Am,2019,57(3):501~518. [4] Liu DS, Wang SL, Li JM,et al. Allicin improves carotid artery intima-media thickness in coronary artery disease patients with hyperhomocysteinemia[J].Exp Ther Med,2017 ,14(2):1722~1726. [5] Wang R,Wang Y, Mu N,et al.Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice[J].Lab Invest,2017,97(8):922~934. [6] 贾贤达,杨庆华,茹建平,等.H型高血压患者血浆炎性因子及血流动力学的变化[J].宁夏医科大学学报,2017,39(2):230~232. [7] 刘长春,孙莹,汪琪,等.H型高血压患者血浆同型半胱氨酸水平与脑血管血流动力学参数的关系[J].中华实用诊断与治疗杂志,2017,31(9):862~864.