Effect of Oxygen Driven Atomization Inhalation Combined with Ventilator on Acute Heart Failure and the Influence of Blood Gas Index and Inflammatory Factors
HUANG Zhengzhuang, YAN Huaixing, LI Yaofei
Nanning First People's Hospital, Guangxi Nanning 530022, China
Abstract：Objective: To study the rescue effect oxygen-driven nebulization inhalation combined with ventilator on blood gas index and inflammatory factors in patients with acute heart failure. Methods: 65 patients of chronic renal failure were divided into 35 cases in the observation group, from January 2016 to January 2019 in our hospital. The 30 cases in the control group by the simple random number table, On the basis of routine treatment, the control group was treated with non-invasive ventilator, while the observation group was combined with oxygen-driven nebulization inhalation, they continuous treatment for 7 days. The clinical efficacy, the changes of blood gas index, inflammatory factors, cardiac function index and adverse reactions were compared between the two groups. Results: After treatment, the total effective rate of the observation group was significantly higher than the control group (P＜0.05). The blood gas indexe arterial partial pressure of carbon dioxide (PaCO2), arterial partial pressure of oxygen (PaO2), arterial oxygen saturation (SaO2), inflammatory factor high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), cardiac function index N-terminal pro-brain natriuretic peptide (NT-proBNP), heart rate (HR), stroke volume (SV), left ventricular ejection fraction (LVEF) of the two groups, there were significant differences between groups and at interblock and different time points(P＜0.05); The above indicators have interaction among interblock and different time points(P＜0.05); The difference before and after treatment in the observation group was greater than the control group (P＜0.05); There was no significant difference in adverse reactions between the two groups(P＞0.05). Conclusion: Oxygen-driven nebulization inhalation combined with ventilator is well for acute heart failure, which can effectively improveimprove the expression of blood gas indicators and inflammatory factors, promote the recovery of cardiac function, and has good safety, it's worthy of application and promotion.
黄正壮, 颜怀兴, 李耀飞. 氧气驱动雾化吸入联合呼吸机对急性心力衰竭的救治效果及血气指标炎症因子的影响[J]. 河北医学, 2020, 26(4): 553-558.
HUANG Zhengzhuang, YAN Huaixing, LI Yaofei. Effect of Oxygen Driven Atomization Inhalation Combined with Ventilator on Acute Heart Failure and the Influence of Blood Gas Index and Inflammatory Factors. HeBei Med, 2020, 26(4): 553-558.
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2020, Vol. 26 
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