Abstract：Objective: To observe the effects of stereotactic targeting minimally invasive surgery on perioperative indexes and prognosis in patients with brain tumors. Methods: The clinical data of 152 patients with brain tumors were retrospectively analyzed. According to the treatment procedures, they were divided into stereotactic targeting minimally invasive surgery group (study group, n=84) and conventional craniotomy group (control group, n=68). The operation condition was observed. The patients were followed up for 1 year after operation, and the improvements of neurological function [neurological impairment score (CCD)] and activity of daily life (ADL) were compared between the two groups before and after treatment. Survival rate and recurrence rate at 1 year after operation and occurrence of complications were observed. Results: The operation condition in study group was superior to that in control group (P<0.05). At 1 year after operation, the CCS scores in the two groups were decreased compared with those before operation, and the score in study group was lower than that in control group (P<0.05). The ADL scores were increased compared with those before operation, and the score in study group was higher than that in control group (P<0.05). The survival rate at 1 year after operation in study group was higher than that in control group (P<0.05) while the recurrence rate was lower than that in control group (P<0.05). The incidence rate of complications in study group was lower than that in control group (P<0.05). Conclusions: Compared with traditional craniotomy, stereotactic targeting minimally invasive surgery for brain tumors can improve the operation condition, promote the recovery of neurological function and activity of daily life, improve safety, and effectively improve the prognosis, therefore it is more advantageous.
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2020, Vol. 26 
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