Abstract：Objective:To observe the efficacy of addition and subtraction of Sanren decoction and Ermiao powder combined with western medicine in the treatment of yin deficiency and dampnesstype of xerophthalmia. Methods:82 patients (164 eyes) with xerophthalmia admitted to our hospital from June 2016 to December 2018 were selected. According to the random number table method, the patients were divided into observation group and control group, with 41 cases (82 eyes) in each group. Control group was given sodium hyaluronate eye drops for external use, and observation group was given addition and subtraction of Sanren decoction and Ermiao powder orally on the basis of control group. After 1 month of treatment, the TCM syndromes scores and efficacy index, objective indicators [Schirmer I test (SIt), break-up time (BUT) of tear film, corneal fluorescein staining (FL)], visual parameters [Strehl ratio (SR), objective scatter index (OSI)] and clinical efficacy were compared between the two groups after 1 month of treatment. Results: After 1 month of treatment, the symptoms scores in observation group were significantly lower than those in control group (P<0.05), and the SIt and BUT in observation group were significantly higher than those in control group while the FL was significantly lower than that in control group (P<0.05), and the SR was significantly higher than that in control group while the OSI was significantly lower than that in control group (P<0.05), and the differences of symptoms scores, SIt, BUT, FL, SR and OSI before and after treatment in observation group were greater than those in control group (P<0.05). The total effective rate in observation group was significantly higher than that in control group (95.12% vs 74.39%) (P<0.05). Conclusions:Sanren Decoction and Ermiao Powder combined with western medicine can better alleviate the symptoms of traditional Chinese medicine, improve the stability of tear film and visual quality, and improve the clinical efficacy.
许婷, 杨丽颖, 郭铁柱. 三仁汤与二妙散加减联合西药治疗阴虚夹湿型干眼症的疗效观察[J]. 河北医学, 2019, 25(8): 1405-1408.
XU Ting, YANG Liying, GUO Tiezhu. Therapeutic Effect of Sanren Decoction and Ermiao Powder combined with Western Medicine on Dry Eye of Yin Deficiency and Dampness. HeBei Med, 2019, 25(8): 1405-1408.
2019, Vol. 25 
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