Abstract：Objective: To explore the effect of collagen sponge in preventing postoperative bleeding and incision adhesion after thyroidectomy. Methods: 98 patients with thyroid surgery, from October 2017 to June 2018, were randomly divided into two groups: observation group and control group. In the observation group, after resection of the lesion, the bleeding was completely stopped by ultrasonic scalpel and bipolar electrocoagulation forceps, and collagen sponge was placed between the surgical wound and anterior cervical muscle group. In the control group, collagen sponge was not placed after complete hemostasis with ultrasonic scalpel and bipolar electrocoagulation forceps. The drainage volume of negative pressure drainage tube and the adhesion of incision and blood oozing were observed after operation. Results: The negative pressure drainage volume of the observation group was 14.64±6.18 ml 24 hours after operation, which was lower than that of the control group (36.68±9.28 ml) , with difference statistically significant(p<0.05). The negative pressure drainage volume of the observation group was 38.10±7.29ml 48 hours after operation, which was lower than that of the control group (56.12±8.67ml) , with difference statistically significant(p<0.05). The incidence of blood seepage was 4.08 % in the post-operative group, which was lower than 16.33 % in the control group. The difference was statistically significant.(p<0.05); The synchronous neck movement rate of the observation group was 10.20%, three months after operation, which was significantly lower than that of the control group (26.53%), with difference statistically significant(p<0.05). Conclusion: The application of collagen sponge in thyroidectomy can effectively prevent postoperative bleeding and incision adhesion, reduce the risk of postoperative bleeding, reduce the incidence of incision adhesion, and has good clinical application value.
2019, Vol. 25 
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