Abstract：Objective: To investigate the effect of hemoperfusion combined with hemodialysis on renal function and T-lymphocyte levels in patients with uremia. Methods: 100 patients with uremia were randomly divided into observation group and control group, with 50 cases in each group. Control group were received hemodialysis and observation group were received hemoperfusion combined with hemodialysis. After 6 months of treatment, the changes of clinical symptoms and quality of life were observed. The indexes of renal function and T-lymphocyte levels were detected before and after treatment. Results: The clinical symptoms in two group were significantly improved after treatment, while the occurrence rates of skin pruritus, dizziness, headache, inappetence and hypertension in observation group were significantly lower than those in control group (P<0.05). The scores of SF-36 in two groups after treatment were increased and the scores of RE, MH, SF, BP, VT and GH in observation group were higher than those in control group (P<0.05). The levels of Scr, BUN and β2-MG level in observation group were lower than those in control group, while the CD3+, CD4+ and CD4+/CD8+ level was significantly higher than control group (P<0.05). Conclusion: Hemoperfusion combined with hemodialysis is helpful to improve the life quality of patients with uremia. It can improve the renal function and immunologic function.
宋培. 血液灌流联合血液透析对尿毒症患者肾功能及T淋巴细胞水平的影响[J]. 河北医学, 2019, 25(8): 1253-1256.
SONG Pei. Effect of Hemoperfusion combined with Hemodialysis on Renal Function and T-lymphocyte Levels in Patients with Uremia. HeBei Med, 2019, 25(8): 1253-1256.
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2019, Vol. 25 
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