Abstract：Objective: To study the clinical efficacy of self-made Qinggan Lishi decoction in the treatment of patients with cervical cancer chemotherapy. Methods: 86 patients with cervical cancer chemotherapy who were admitted to our hospital from January 2016 to July 2017 were randomly divided into control group (43 cases) and observation group (43 cases). Control group was given paclitaxel/irinotecan chemotherapy regimen, and observation group was given self-made Qinggan Lishi decoction on the basis of control group. After 6 w of treatment, the tumor diameter, time required for chemotherapy, treatment effects, serum tumor markers levels, immune function, quality of life and adverse reactions were evaluated and analyzed in the two groups. Results: The tumor diameter in observation group after treatment was significantly reduced, and the total effective rate of treatment was higher than that in control group (81.39% vs 72.09%) (P<0.05). The serum levels of carbohydrate antigen 125 (CA125), squamous cell carcinoma antigen (SCCA) and carcinoembryonic antigen (CEA) were significantly decreased in observation group after treatment (P<0.05). The levels of immunoglobulin G ((IgG), immunoglobulin M (IgM) and immunoglobulin A (IgA), blood CD3+ and CD4+ cell ratios and CD4+/CD8+ ratio in the blood were increased significantly in observation group (P<0.05). The SF-36 scores in observation group after treatment were significantly higher than those in control group (P<0.05), and the incidence rate of adverse reactions of grade II-III was significantly lower than that in control group (P<0.05). The local recurrence rate and distant metastasis rate within 1 year of treatment were 4.65% and 2.33% in observation group, which were lower than those in control group with 11.63% and 4.65% (P<0.05). Conclusions: Self-made Qinggan Lishi decoction can effectively improve the clinical treatment effects of patients with cervical cancer chemotherapy.
左敏芳. 自拟清肝利湿汤治疗宫颈癌化疗患者的临床疗效[J]. 河北医学, 2019, 25(7): 1226-1230.
ZUO Minfang. Clinical Efficacy of Self-made Qinggan Lishi Decoction in the treatment of Patients with Cervical Cancer Chemotherapy. HeBei Med, 2019, 25(7): 1226-1230.
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2019, Vol. 25 
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