Abstract：Objective: To investigate the safety and efficacy of laparoscopic pancreaticoduodenectomy combined with accelerated rehabilitation surgery. Methods: 84 patients undergoing pancreaticoduodenectomy admitted to the hospital were enrolled according to the surgical procedure. 42 patients in the control group underwent open pancreaticoduodenectomy. 42 cases underwent laparoscopic pancreaticoduodenectomy. The safety and efficacy of the two groups of treatments were compared. Results: The operation time of the observation group was (543.8±59.2) min, which was higher than that of the control group. The intraoperative blood loss (191.5±56.2) mL in the observation group was 30.00% in the transfusion patients, which was lower than the control group (P<0.05). The VAS scores of the observation group at 2h, 6h and 12h after operation were lower than those of the control group (P<0.05). The delay of gastric emptying in the observation group was 6.0%, which was lower than that of the control group (26.0%) (P<0.05). The intensive care unit (2.4±0.8) days and the hospitalization time (14.6±1.3) days were shorter than the control group (P<0.05). The number of positive lymph nodes in the observation group was 1.0±0.4, the ratio of vascular invasion was 8.0%, the diameter of tumor was (2.7±0.6) cm, and the proportion of middle/middle-lower differentiated tumor was 42.0%, which was lower than that of the control group (P<0.05). Conclusion: Laparoscopic pancreaticoduodenectomy combined with accelerated rehabilitation surgery is safe and effective, which is worthy of promotion.
2019, Vol. 25 
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