Abstract：Objective: To explore the effect and analysis of interventional technique in the treatment of deep venous thrombosis after lower extremity surgery. Methods: 136 patients with deep venous thrombosis of lower extremities who were treated in our hospital from January 2010 to December 2018 were divided into observation group and control group according to the digital table method, 68 cases in each group. The control group was treated with conventional anticoagulation therapy, while the observation group was treated with catheter thrombolytic interventional therapy on the basis of the control group. The perimeter of one healthy limb, popliteal vein blood flow velocity and intravascular diameter, plasma PAl-1 level and clinical biochemical indexes were compared and analyzed between the two groups. Results: After treatment, the effective rate of the observation group was 86.76%, significantly higher than that of the control group (67.65% (P > 0.05). Before treatment, there were no significant differences in the menstrual difference between the thighs and legs, popliteal vein internal diameter and blood flow velocity between the two groups (P > 0.05). After treatment, the menstrual changes of the legs of the two groups were significantly reduced. The comparison between the two groups showed that the experimental group was significantly smaller than that of the control group, with statistical significance. Significance (P < 0.05); experimental group and control group had significant differences in vascular diameter and blood flow velocity (P < 0.05). After treatment, PAI-1 in the experimental group was significantly higher than that in the control group, while t-PA was significantly lower than that in the control group, with statistical significance (P < 0.05). The levels of Lp (a), D-D, FIB, AT, PS and P C in the experimental group were lower than those in the control group, with significant difference (P < 0.05). The PLT index in the experimental group was significantly higher than that in the control group (P < 0.05). Although the MPV index in the experimental group was higher than that in the control group, there was no statistical significance (P > 0.05). Conclusion: Catheter thrombolysis interventional technique can effectively remove intraluminal thrombosis in the treatment of deep venous thrombosis after lower limb surgery, and its effect is better than anticoagulation therapy alone, which is worthy of clinical promotion.
[1] Alper E C, Ip I K, Balthazar P, et al. Risk stratification model: lower-extremity ultrasonography for hospitalized patients with suspected deep vein thrombosis[J]. Journal of General Internal Medicine, 2017, 33(14):1~5. [2] Sundar G , Keshava S , Moses V , et al. Outcomes of catheter-directed treatment of lower extremity deep vein thrombosis of patients presenting to a tertiary care hospital[J]. Indian Journal of Radiology & Imaging, 2016, 26(1):73~80. [3] Jiang K , Li X Q , Sang H F , et al. Mid-term outcome of endovascular treatment for acute lower extremity deep venous thrombosis[J]. Phlebology, 2017, 32(3):200~206. [4] Shi W Y , Gu J P , Liu C J , et al. Endovascular treatment for iliac vein compression syndrome with or without lower extremity deep vein thrombosis: A retrospective study on mid-term in-stent patency from a single center[J]. European Journal of Radiology, 2016, 85(1):7~14. [5] 王海涛,于志海,涂灿,等.下肢深静脉血栓介入性溶栓治疗疗效分析[J].中国现代医生,2017,(31):31~34,40. [6] 陈文红.D-二聚体异常患者下肢深静脉血栓的预防措施及效果分析[J].基层医学论坛,2016,(24):3438~3440. [7] Duan P F , Ni C F . Randomized study of different approaches for catheter-directed thrombolysis for lower-extremity acute deep venous thrombosis[J]. Journal of the Formosan Medical Association, 2016, 115(8):652~657. [8] 邬文景,王迪,沈俊晔,等.中西医结合治疗下肢深静脉血栓形成疗效及彩色多普勒超声观察[J].中华中医药学刊,2017,(10):217~219.
2019, Vol. 25 
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